高压氧对颅脑损伤患者C-反应蛋白和血糖的影响

Study on the effect of serum C-reactive protein and blood glucose of patients with craniocerebral injury by the HBO ttreatment

目的探讨高压氧治疗对中重型颅脑损伤后血糖和C-反应蛋白的影响。方法根据入院时首次GCS计分，符合人选标准的84例颅脑损伤患者中中型颅脑损伤（G1）44例、重型颅脑损伤（G2）40例，再分别随机将G1、G2组中的患者分为治疗组和对照组，治疗组给予常规治疗及高压氧治疗，对照组仅常规治疗。分别测定全部患者入院24小时内、高压氧治疗第一个疗程和高压氧治疗第二个疗程后的清晨血糖和C-反应蛋白值，并进行对比分析。结果颅脑损伤后空腹血糖和C-反应蛋白的增高与颅脑损伤程度均成正相关关系，且空腹血糖和C-反应蛋白两者之间也成正相关性。结论测定空腹血糖和C-反应蛋白有助于了解颅脑损伤的病情。高压氧治疗可以降低空腹血糖和C-反应蛋白。

Objective To explore the effect of serum C-reactive protein and blood glucose of cranincerebral injury patients by the hyperbaric oxygen （ HBO ）treatment. Methods After the determination, the normal control group were with 20 cases, and the medium group （ G 1 ） with 44 cases, the severe group （ G2 ） with 40 cases. Craniocerebral injury patients were given the hyperbaric oxygen treatment within 24 hours admission in the first course of treatment and hyperbaric oxygen treatment in the early morning after the second course of blood glucose and C-reactive protein values. Results Fasting blood glucose after head injury and elevated C-reactive protein levels with craniocerebral injury were positively correlated, and fasting blood glucose and C-reactive protein also had the positive correlation.Conclusions Fasting blood glucose and C-reactive protein can help to understand the condition of craniocerebral injury patients.And the hyperbaric oxygen treatment can reduce the fasting blood glucose and C-reactive protein.