中药穴位敷贴治疗支气管哮喘的临床研究

Clinical Study of Bronchial Asthma Treated with Acupoint Application Therapy

目的:观察中药穴位敷贴疗法对支气管哮喘缓解期的生存质量及临床症状的影响。方法:将来自于作者单位的两家医院的50例患者随机分为治疗组33例和对照组17例。治疗组用胡椒、白芥子、细辛、白芷、半枫荷、姜油、姜汁等,对照组用姜汁配红米、黑米、玉米等,分别制成药饼敷贴穴位。两组均选用大椎、肾俞、肺俞、脾俞(第1组穴)和天突、膻中、气海、关元、足三里(第2组穴)穴位交替进行治疗,每周敷贴2次,共贴8次。观察治疗前后AQLQ表(包括日常活动、哮喘症状和环境影响)和日夜间症状记录表评定患者生存质量和临床症候的变化;测定治疗前后第一秒用力呼气量(FEV1)占预计值的百分比(FEV1%)及第一秒用力呼气量占用力肺活量(FVC)的百分比(FEV1/FVC)。结果:①治疗组AQLQ总分、日常活动及环境影响评分治疗后与对照组比较均有统计学差异(P<0.05),治疗组在治疗后AQLQ表中各部分评分值及总分均较治疗前有明显提高(P<0.05);②治疗组在治疗后日、夜间症状评分均较治疗前明显降低(p<0.05),两组在治疗后日、夜间症状评分有统计学差异(P<0.05);③两组FEV1%及FEV1/FVC比值治疗后比较无统计学差异(P>0.05),治疗组治疗前后比较也无统计学差异(P>0.05)。结论:中药穴位敷贴疗法可以有效地提高支气管哮喘患者的生存质量及减少支气管哮喘患者的发作次数。

Objective：To observe the effect on clinical symptom and quality of life of bronchial asthma catabasis with acupoint application therapy. Methods：50 remission stage bronchial asthma cases were randomized to two groups： ①treatment group （ group A, n = 33 ）, received traditional Chinese medicine eake（ ginger juice and ginger oil mixing with herbal powder of pepper, Semen Sinapis, Herba Asari, Radix Angelicae dahuricae and Radix pterospermi Heteropbyllum） ;②control group （group B ,n = 17 ） received medicine cake（ ginger juice mixing with herbal powder of black rice,red rice,corn）. Two groups were treated ahernativly with aeupoint application therapy on acupoint group 1 （ Dazhui, Shenshu, Feishu, Pishu） and acupoint group 2 （ Tiantu, Tanzhong, Qihai , Guanyuan, Zusanli）. The therapies were twice per week,8 times in total. Obseving the changes of their sings and symptoms and quality of life before and after treatment by AQLQ（ include ability of daily activities ,invironment influence and clinical symptom）. Determine the change of the forced expiratory volume in the first second （ FEV1 ） accounting for the predicted vital capacity percentage （ FEV 1% ） and FEV1 taking forced vital capacity （FVC） percentage （FEV1/FVC）. Results ： ①The scores of ability of daily activities,invironment influence,clinical symptom and the total score of AQLQ obviously enhanced post treatment in group A（P 〈0.01 ）. Except clinical symptom, the differences were significant （P 〈 0.05 ） between group A and group B. ②The scores of day＇ s symptom and night＇ s symptom obviously declined post treatment in group A. The differences were significant （ P 〈 0.05 ） between group A and group B ＆ pre and post treatment of group A （ P 〈 0.05 ）. ③There was no significant difference between group A and group B on FEV1% and FEVI/FVC （P 〉 0. 05）. Conclusion ： Chinese medicine aeupoint application therapy not only can increase effectively the quality of life of of the asthma patients but also can decrease the frequency of asthma attacks.