早期高危子宫内膜癌术后辅助化疗临床分析

Clinical analysis of postoperative chemotherapy on patients with high-risk early stage endometrial cancer

为了探讨有高危因素的早期子宫内膜癌患者术后辅助化疗对其预后的影响,选择1998-05-2009-03具有高危因素的早期子宫内膜癌患者60例为化疗组,60例相同期别未化疗者为对照组,观察两组患者的5年生存率并进行比较与分析。化疗组患者的5年生存率为93%,对照组为80%,两组比较差异有统计学意义,P<0.05。初步研究结果提示,对有高危因素的早期子宫内膜癌患者术后辅助化疗能改善患者的预后,提高5年生存率。

The objective of this study was to investigate the effects of adjuvant chemotherapy for patients with high risk early stage endometrial cancer. Form May 1998 to Mar 2009, patients with high-risk endometrial eancer were devided into two groups, based with postoperative adjuvant chemotherapy as ACT group（60 cases）, without adjuvant chemotherapy as control group（60 cases）, The 5-year survival rates of two groups were observed. The 5-year survival rate in the ACT group was significantly higher than that in contral group （93 G and 80 G） signifiantly（P〈 0.05）. In conclusion, postoperative chemotherapy maybe imporve the prognosis of patients with hlgh-risk early stage endometrial cancer,and prolong the 5-year survival rate.