加用孟鲁司特钠治疗咳嗽变异性哮喘效果观察

The Clinical Observation of Montelukast Turner in Treating Cough Variant Asthma (CVA)

目的:探讨加用孟鲁司特钠治疗咳嗽变异性哮喘的临床效果。方法:将2008年5～12月在我院就诊的80例咳嗽变异性哮喘患者随机分为观察组和对照组,对照组用常规方法治疗,观察组在此基础上加用孟鲁司特钠。结果:观察组治疗总有效率为92.5%,对照组为72.5%,两组比较有显著性差异(P<0.05);治疗后两组患者肺功能测定与治疗前比较,1min呼吸用力容积(FEV1)、用力肺活量(FVC)和最大呼气流量(PEFR)值均有改善,但观察组肺功能改善要好于对照组。结论:孟鲁司特钠治疗咳嗽变异性哮喘能明显提高有效率,改善肺功能,不失为治疗咳嗽变异性哮喘的理想药物。

Objective：To observe the Clinical results of Montelukast Turner in treating Cough Variant Asthma （CVA）.Methods：Selected 80 Patients with CVA,and were treated from May 2008 to Dec 2008 in our hospital.They were divided into two groups randomly：One was control group,the patients were given routine treatment;the other was observation group,the patients were given the medicine of Montelukast Turner besides routine treatments.Results：The total efficient of observation group was 92.5%,while control group was 7.5%.Consequently the difference between two groups had statistical significance（P 0.05）;As determinated patients＇ pulmonary function in the two groups and comparing it before and after treating,we found that the value of FEV1、FVC and PEFR were all improved,difference of the observation had statistical significance（P 0.05）,while the other group didn＇t have（P 0.05）.Conclusion：The effect of Montelukast Turner of treating CVA is very obvious,Montelukast Turner can improve patients＇ pulmonary function,but it is also a kind of effevtive medicine for treating CVA.