某高校教职工脂肪肝患病危险因素及其与代谢综合征关系分析

Risk Factors of Fatty Liver and Its Relationship With Metabolic Syndrome Among Staff of One University

目的探讨某高校教职工脂肪肝发生的危险因素及其与代谢综合征的关系,为高校教职工脂肪肝的预防提供依据。方法采用横断面研究方法,以沈阳市某大学1 063名在职及退休教职工为研究对象,进行人体测量、血液检测及腹部B超检查。结果教职工脂肪肝检出率为34.6%,男性(40.5%)显著高于女性(27.6%)(P<0.01)。调整年龄、性别后,超重、肥胖、中心型肥胖、高三酰甘油、高胆固醇、高血糖者患脂肪肝的危险度分别是正常者的14.32,3.45,2.65,3.14,1.71,1.71倍(P值均<0.05),且高三酰甘油、高胆固醇、高血糖的作用独立于肥胖。调整年龄、性别、体质量指数后,脂肪肝者患代谢综合征的危险度是正常者的3.44倍(P<0.05)。结论肥胖、高三酰甘油、高胆固醇、高血糖是脂肪肝的独立危险因素,罹患脂肪肝患代谢综合征的危险度较高。

Objective To explore risk factors of fatty liver and its relationship with metabolic syndrome among staff of one university, in order to provide basis for prevention of fatty liver in university. Methods By using cross-sectional study method, anthropometric measurements, blood sample tests and abdominal uhrasonography were taken among 1 063 in-service and reiired staff of one university in Sbenyang. Results The preva- lence rate of fatty liver was 34.6%, male＇s{ 40.5% ） was significantly higher than female＇ s （ 27.6%） （ P 〈 0. 01 ）. After adjustment for age and sex, persons who were overweight, obesity, central obesity, high triglyceride, hypereholesterolemia and hyperglycemia had more risk to suffer fatty liver than normal person, the multiples were 14.32, 3.45, 2.65, 3.14, 1.71 and 1.71 （P〈0.05）. Meanwhile the effects of high triglyceride, hy- percholesterolemia and hyperglycemia were independent of obesity. After adjustment for age, sex and body mass index, person with fatty liver had more risk to suffer metabolic syndrome than normal person, the multiple was 3.44 （ P 〈 0.05 ）. Conclusion Obesity, high triglyceride, hypereholesterolemia and hyperglycemia are independent risk factors for fatty liver, and people with fatty liver are at high risk to suffer metabolic syndrome.