思密达联合血竭治疗溃疡性结肠炎的临床研究

Clinical Studies on Effects of Dragon’s Blood and Smecta and Retention Enema on Ulcerative Colitis

将100例轻、中度远段活动期溃疡性结肠炎(UC)患者,随机分为治疗组56例和对照组44例,治疗组采用思密达和血竭分别加温生理盐水保留灌肠,对照组采用口服柳氮磺胺呲啶(SASP)和地塞米松2 mg联合甲硝唑1 g保留灌肠,疗程均为4周.结果显示,治疗组和对照组总有效率分别为92.9%和79.6%(P<0.05),且治疗期间治疗组不良反应明显少于对照组,表明思密达联合血竭保留灌肠治疗轻、中度远段活动期UC疗效满意.

In order to examine clinical efficacy of Dragon＇s Blood and Smecta and retention enema on slight or moderate distal active ulcerative colitis（UC）, 100 patients with slight or moderate distal active UC were randomly allocated and divided into treatment group of 56 cases and control group of 44 cases. Subjects in treatment group were treated with either Dragon＇s Blood or Smecta, in addition to warm normal saline and retention enema. Subjects in control grout）were treated with regular oral dose of Sulphasalazinc （SASP）, along with retention-enerna with 2 mg of DX and 1 g of metronidazole. The period of treatment was 4 weeks. As a rcsuh, the total percentagc of efficiency of treatment group and control group were 92.9 % and 79.6 % （P〈 0.05）, respectively. Treatment group had less adverse reaction than control group. The result indicates that treatment of Dragon＇s Blood and Smecta has been effective on slight or moderate distal active UC.