C-反应蛋白与急性脑梗死相关性研究分析

The relationship between C-reactive protein and acute cerebral infarction

目的研究血清中C-反应蛋白(CRP)水平与急性脑梗死的关系。方法测定110例急性脑梗死患者和96例健康对照者血清CRP含量,并根据梗死灶面积大小分组,分析各组与CRP水平的相关性。结果急性脑梗死患者平均CRP浓度为(11.2±2.38)mg/L,而对照组为(2.32±0.84)mg/L,两组比较有显著性差异(P<0.05)。小梗死灶组平均CRP浓度为(4.70±1.52)mg/L,中梗死灶组平均CRP浓度为(9.21±2.23)mg/L,与小梗死灶组比较,有显著性差异(P<0.05),大梗死灶组平均CRP浓度为(17.46±3.68)mg/L,与小梗死灶组及中梗死灶组比较,有显著性差异(P<0.05)。结论血清CRP水平增高与脑梗死的发生和严重程度有密切关系。

Objective To study the relationship between the levels of C-reactive protein （CRP） and acute cerebral infarction （ACI）.Methods The serum levels of CRP in 110 patients and 96 healthy persons were determined.At the same time,the changes of CRP were compared with patients of different infarction size.Results The level of CRP in patients with ACI was（11.2±2.38）mg/L,obviously significantly compared with control group of （2.32±0.84）mg/L（P〈0.05）.The average CRP was （4.70 ±1.52）mg/L in small infarction group,compared with （9.21 ±2.23）mg/L in middle infarction group,the difference was significant （P〈0.05）.The average CRP of large infarction group was （4.70 ±1.52）mg/L,which showed a significantly difference compared with small and middle group （P〈0.05）.Conclusion The increasing serum levels of CRP were connected with the occurrence and severity of cerebral infarction.