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不同禽源新城疫病毒强毒株对鹅的致病性研究 被引量:6

Pathogenicity of Virulent Newcastle Disease Virus Strains from Different Avian Species in Geese
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摘要 分别采用鸽、鸡、鸭、鹅源新城疫病毒(NDV)强毒株和NDV国内标准强毒株F48E8进行鹅的人工感染试验,对感染鹅的临床症状、增重、抗体水平和排毒情况进行详细观察,探讨不同禽源NDV强毒株对鹅的致病性以及鹅在家禽新城疫(ND)流行中的意义。结果表明,鸽源强毒株JSP0204对鹅无致病性或致病性很弱,感染鹅未表现临床症状,增重也未受到显著影响(P>0.05)。而鸡源JSC0804、鸭源JSD0812、鹅源JSG0210和F48E8株均可致鹅发病和死亡,尤以鸭源JSD0812和F48E8株致病性最强,致死率高达100%。所有感染鹅均可排毒,排毒时间因毒株不同而异。研究结果表明目前流行的NDV强毒株对鹅的致病性普遍增强,并进一步证实鹅在ND流行病学中具有重要的作用。 The pigeon,chicken,duck,and goose origin virulent Newcastle disease virus (NDV) strains and Chinese standard virulent NDV strain F48E8 were used to infect geese experimentally. The clinical signs,weight gain,antibody response,and virus shedding of infected geese were determined. The pathogenicity of virulent NDV strains of different avian origin in geese and the importance of geese in the epidemics of Newcastle disease (ND) were investigated. The ( pigeon origin JSP0204 strain had low or no pathogenicity to geese;they produced neither clinical signs of the disease nor obvious adverse effect on growth of infected geese (P〉0.05). Other strains, including chicken origin JSC0804 strain,duck origin JSD0812 strain,goose origin JSG0210 strain and F48E8 strain,could cause illness and death,both JSD0812 and F48E8 strains were highly pathogenic for goslings;they caused 100% mortality. Virus shedding was detectable in all infected goslings,but its period varied with strain infected. The results indicated that the pathogenicity of current epidemic virulent NDV strains for geese have generally inereased,and further confirmed that the geese could play an important role in the epidemiology of ND.
出处 《中国家禽》 北大核心 2010年第4期26-29,共4页 China Poultry
基金 江苏省科技计划项目(BM2008171) 江苏省"333高层次人才培养工程"科研项目(苏人才办[2007]16号) 国家公益性行业(农业)科研专项经费项目(200803020)
关键词 新城疫病毒 强毒株 致病性 排毒 goose Newcastle disease virus virulent strain pathogenicity virus shedding
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