摘要
压力性尿失禁是泌尿外科常见病,大多数学者认为年龄、体质量指数、妇科手术史、反复泌尿道感染为尿失禁的高危因素。目前关于压力性尿失禁的研究很多,盆底组织胶原降解增加引起盆底组织支持力减弱是压力性尿失禁的重要发病机制。对盆底组织分子水平的研究,有利于更进一步明确压力性尿失禁的病因,为寻找更好的预防和治疗方法提供了新的思路,现就目前的分子研究水平热点予以综述。
Stress urinary incontinence(SUI)is a common disease in the urinary surgery.Many researchers believe that age,body mass index,history of gynecologic surgery,and repeated urinary tract infections are the high risk factors for SUI.At present,a lot of researches on stress urinary incontinence reveal that collagen degradation in pelvic organ can weaken the supportive role of this tissue,which is the pathogenesis of SUI.Pelvic organ studies at the molecular level can be helpful to investigate the etiology of stress incontinence,and can provide a new way in the research of better prevention and treatment of SUI.This article reviewed the current hotspot on molecular level of pelvic tissue.
出处
《医学综述》
2010年第4期523-526,共4页
Medical Recapitulate
关键词
压力性尿失禁
结缔组织
分子水平
Stress urinary incontinence
Connective tissue
Molecular level