中国西部地区乳腺癌诊断年龄的抽样分析及中美对比研究

Diagnostic age of breast cancer in Northwest China and compared with the data of USA

目的:研究中国乳腺癌诊断年龄并比较与美国乳腺癌诊断年龄的差异。方法:收集从1975年-2005年间西京医院收治的乳腺癌病例,对诊断年龄分布进行统计分析,并与美国Surveillance Epidemiology End Results(SEER)数据库数据比较。结果:获得乳腺癌患者3074例,诊断年龄范围17-91岁,平均48.65岁;高峰集中在45-54岁年龄段,共1006例,占总患病人数的32.73%;<35岁的年轻型乳腺癌297例,占9.67%。而美国SEER数据显示,2002年-2005年间美国乳腺癌平均诊断年龄为61岁;高峰集中在55-64岁年龄段,占总患病人数的23.7%;<35岁的年轻型乳腺癌占总患病人数1.9%。同期中美乳腺癌平均诊断年龄及总体年龄分布存在显著差异(P<0.01)。结论:我国乳腺癌患者的诊断年龄较美国年轻,与美国SEER公布数据相比,乳腺癌诊断平均年龄和高峰年龄段明显提前,年轻型乳腺癌患者所占比例明显增高。

Objective：To analyze the diagnostic age of breast cancer in China and the difference of diagnostic age between China and America. Methods： The clinical records of patients with breast cancer in 1975 to 2005 were collected in Xijing Hospital. Diagnostic age of breast cancer was analyzed and compared with data from Surveillance Epidemiology End Results（SEER） of USA. Results：There were 3074 patients of breast cancer during the period of 1975 to 2005 in Xijing Hospital. The diagnostic age of these patients ranged from 17 to 91 and average age was 48.65. The peak diagnostic age was from 45 to 54 which were consisted of 1006 patients and occupied 32.73 percent. There were 297 patients who were younger than 35 years old ,which occupied about 9.67 percent. While the data of SEER showed that the average diagnostic age of breast cancer in USA during the period of 2002 to 2005 was 61. The peak diagnostic age was from 55 to 64 ,which occupied 23.7 percent. The patients who were younger than 35 occupied only 1.9 percent. There were obviously difference between Chinese and American breast cancer patients on both of the diagnostic age and the distribution of whole diagnostic age （P 〈0.01 ）. Conclusion.Both of the average diagnostic age and peak period of breast cancer in China were younger than that in USA. The percentage of young breast cancer in China is obviously higher than that in USA.