出生时机体营养状况对成年后患代谢综合征影响的研究进展

Influence of nutritional status at birth on development of metabolic syndrome in adulthood:an advance

随着经济水平的提高,全球老龄化现象的日渐加剧,减少老年人慢性病发病率,提高社会的整体生活质量,是当今医学工作者着力研究的重点。成年后的机体在细胞、组织以及器官等各方面都存在不同程度的不可逆转性。"胎源假说"认为生命早期营养不良与成年后患代谢综合征(metabolic syndrome,MS)关系密切,如果在生命早期就采取干预措施,应该能够减少或避免成年后一系列疾病的发生。因此,本文就生命早期营养不良与MS各组分(肥胖、高血糖、高血压及高血脂等)的关系作一综述。

Aging as a global problem is intensifying with the development of economy;reducing the chronic diseases in the elderly and improving the life quality of the whole population are a study focus of medical researchers of today.The changes of cells,tissues,and organs in adults are not reversible to different extents.Fetal origin hypothesis believes malnutrition early in life is closely associated with the metabolic syndrome in adults,and if measures is taken at early stage of life,it may reduce or avoid a series of disease in adults.This paper reviews the association of malnutrition at early stage of life with metabolic syndrome（obesity,hyperglycemia,hypertension,and hyperlipemia） in adults.