1例人感染高致病性禽流感死亡病例的流行病学调查

Epidemiological Survey on 1 Human Death Case by Highly Pathogenic Avian Influenza Virus

[目的]为查明人感染高致病性禽流感病例发生的原因,为今后预防和控制人感染高致病性禽流感提供科学依据。[方法]2009年1月26日对该市1例人感染高致病性禽流感患者进行流行病学调查分析。[结果]采集病人的鼻咽拭子和下呼吸道吸取物经广西壮族自治区疾病预防控制中心检测、中国疾病预防控制中心复检,H5N1禽流感病毒核酸阳性。人感染高致病性禽流感为北流市首次发现,经采取预防措施有效地控制了疫情。[结论]该病例感染来源为禽类。加强医务人员的培训和医疗机构不明原因肺炎监测,切断传播途径,采取有效的环境消毒及隔离措施是预防控制人感染高致病性禽流感的主要措施。

[Objective]To find out the causes of 1 human death case infected with highly pathogenic avian influenza virus ,to provide a scientific basis for furture prevention and control of the infection of highly pathogenic avian influenza virus in human. [Mcthods]Epidemiological survey and analysis were conducted for the case infected with highly pathogenic avian influenza virus on 26 January 2009. [Results]Samples of nasopharyngeat swab and secretions of lower respiratory tract were collected and tested in CDC of Guangxi Zhuang Autonomous Region and re-inspected by Chinese Center for Disease Control and Prevention. AIV-RNA was positive. This was the first human case infected with highly pathogenic avian influenza virus in Beiliu city, the epidemic was well controlled after effective prevention measure was taken. [Conclusion] The infection source was avian. The key measures to prevent and control the infection of highly pathogenic avian influenza virus in human were to enhance the training for medical employees and surveillance to unclear pneumonias in medical establishments,cut off the transmission routes and take effective measures of environmental disinfection and separation.