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三七总甙对博来霉素诱导肺纤维化大鼠肺内结缔组织生长因子的影响 被引量:5

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摘要 目的观察三七总苷(PNS)对肺纤维化大鼠肺内结缔组织生长因子(CTGF)的影响。方法气管内注入博莱霉素(BLM)诱导肺纤维化模型,用Western blotting法检测肺内CTGF含量。结果NS组CTGF较少;(BLM+NS)组较NS组明显增多(P<0.01);(BLM+PNS)组较(BLM+NS)组明显减少(P<0.01),并与NS组比较无统计学差异(P>0.05)。结论PNS能阻止肺纤维化形成过程中CTGF的增多。
出处 《中国现代药物应用》 2010年第4期125-125,共1页 Chinese Journal of Modern Drug Application
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