滇乌碱的结构改造

Structural Modification of Yunaconitine

滇乌碱是云南乌头属植物中分布最广、含量最高的一种二萜生物碱成分，但其毒性高。为了充分利用这一丰富的资源，我们用滇乌碱为起始物合成了７个衍生物。本文对衍生物合成的方法及合成产物的光谱数据作了报道。

Yunaconitine, a diterpenoid alkaloid native to Yunnan in the plants of Aconitum species, is the richest in content and the widest in distribution, but its toxicity is high. In order to utilize the rich resource, some structural modification from yunaconitine had been undertaken, and seven derivatives have been got. This paper reports the synthetic ways of these derivatives and their spectra.