摘要
目的探索连续性静脉-静脉血液滤过(CVVH)对顽固性心力衰竭的治疗效果。方法将40例经内科药物保守治疗效果不佳的顽固性心力衰竭患者分为观察组(22例),对照组(18例),观察组予以CVVH治疗,对照组予以保守治疗;观察治疗前后心功能、血液生化、细胞因子浓度以及两组患者28 d死亡率。结果CVVH可明显改善患者的心功能、纠正代谢紊乱,降低炎症细胞因子水平,28 d死亡率由对照组的94.4%降至45.5%(P<0.05)。结论CVVH对顽固性心力衰竭患者是一种迅速而有效的治疗方法,能在短期内缓解临床症状,阻断疾病的恶性循环,为进一步治疗赢得宝贵的时间。
Objective To explore the therapeutic effect of continuous venovenous hemofihration（CVVH） for refractory heart failure. Methods 40 patients with refractory heartfailure were derided into two groups ： observation group（22 cases）and control group （18 cases）. Observation group received CVVH, control group received medical treatment. Cardiac function ,changes of blood biochemistry,cytokine concentration and 28 days mortality were investigated before and after continuous venovenous hemofiltration in patients. Results Compared with control group, the mortality rate decreased （94.5 % vs 45.5 %, P 〈 0.05 ）, and heart function and metabolic disturbance inproved, and seram inflammetory cytolcines decreased significanty in observation group during the 28 day treatment period. Conclu. sion Continuous venovenous hemofihration could be a rapid and effective method in treating patients with refractory heart failure.
出处
《中国临床保健杂志》
CAS
2010年第1期59-61,共3页
Chinese Journal of Clinical Healthcare
