期刊文献+

68例糖尿病肾病患者血清超敏C反应蛋白、血清抗氧化型低密度脂蛋白抗体检测结果分析

68 cases of diabetic nephropathy in patients with high-sensitivity C-reactive protein,serum anti-oxidized low-density lipoprotein antibody test results of analysis
下载PDF
导出
摘要 目的:探讨糖尿病肾病与超敏c反应蛋白(hs-CRP)、抗氧化型低密度脂蛋白(OX-LDL)抗体的关系。方法:测定68例糖尿病肾病患者及50例正常对照组血清超敏C反应蛋白、血清抗氧化型低密度脂蛋白抗体,并将两组结果作对比分析。结果:糖尿病肾病患者血清hs-CRP、血清OX-LDL抗体均高于正常对照组,两组之间差异具有统计学意义(P<0.01)。结论:血清hs-CRP、血清OX-LDL抗体在糖尿病肾病组中明显升高,可作为糖尿病肾病发生、发展的重要指标。 Objective:To investigate the diabetic nephropathy and ultra -sensitive e -reactive protein (hs -CRP), anti -oxidized low- density lipopmtein (OX - LDL) antibodies relationship. 68 patients were measured in patients with diabetic nephropathy and 50 normal control group, serum high - sensitivity C - reactive protein, serum anti - oxidized low - density lipoprotein antibody, and two sets of results were analyzed. Results in patients with diabetic nephropathy serum hs - CRP, serum OX - LDL antibodies were higher than the normal control group, the differences between the two groups was statistically significant (P 〈0.01 ). Conclusion Serum hs - CRP, serum OX - LDL antibodies in diabetic nephropathy group was significantly higher, can be used as diabetic nephropathy, the development of key indicators.
作者 夏和平
出处 《医学信息(中旬刊)》 2010年第2期178-179,共2页 Medical Information Operations Sciences Fascicule
关键词 超敏C反应蛋白 抗氧化型低密度脂蛋白抗体 糖尿病肾病 High- sensitivity e -reactive protein Anti -oxidized low density lipoprotein antibody DN
  • 相关文献

参考文献5

二级参考文献35

  • 1郭翼华,赵凡,陈荣策.超敏C-反应蛋白和视黄醇蛋白的检测在评估糖尿病并发症发生的临床价值[J].现代检验医学杂志,2004,19(4):41-42. 被引量:2
  • 2何冰,韩萍,吕先科.2型糖尿病患者急性时相蛋白与糖尿病肾病的关系[J].中华内分泌代谢杂志,2003,19(4):260-262. 被引量:170
  • 3Hansson GK.Immune and inflammatory mechanisms in the developmment of atherosclerosis[J].Br Hert J,1993,69(Supp l):38-41.
  • 4Devaraj S,Xu DY,Jialai I.C-reactive protein increase plasminogen activator inhibitot-1 expression and activity in human aortic endothelialcells:Inplications for the metabolic syndrome and atherothrombosis[J].Circulation,2003,107(4):398-404.
  • 5Hulthe J,Wikstrand J,Fagerberg B.Relationship between C reactive protein and intima-media thickness in the carotid and femoral arteries and to antibodies against oxidzed low density lipoprotein in healthy men:the atherosclerosis and insulin resistance(AIR) study[J].Clin Sci,2001,100(4):371.
  • 6Rosenfeld ME, Palinski W, Yla-Herttuala S, et al. Arte-riosclerosis, 1990; 10(3): 336-349
  • 7EharaS, UedaM, NarukoT, etal. Circulation, 2001; 103(15): 1955- 1960
  • 8Erkkila AT, Narvancen O, Lehto S, et al. Arterioscler Thromb Vasc Biol, 2000; 20(1): 204-209
  • 9Yasunobu Y, Hayashi K, Shingu T, et al. Atherosclerosis,2001; 155(2): 445-453
  • 10Inoue T, Uchida T, Kamishirado H, et al. J Am Coll Car-diol, 2001; 37(7): 1871-1876

共引文献195

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部