三种方法治疗青春期功能失调性子宫出血的疗效比较

Comparison of therapeutic effects of three methods in the treatment of adolescent dysfunctional uterine bleeding

目的:比较分析三种方法治疗青春期功能失调性子宫出血的临床效果。方法:将我院2006年11月～2008年6月收治的120例青春期功血患者随机分为三组,各40例。A组采用苯甲酸雌二醇、乙烯雌酚、安宫黄体酮治疗,B组采用倍美力、安宫黄体酮治疗,C组采用妈富隆治疗,比较分析三组的临床效果。结果:A、B、C三组的总有效率分别为95.0%、92.5%、97.5%,组间差异无统计学意义(P>0.05);C组的控制出血时间及完全止血时间分别为(42.3±7.2)h、(60.5±5.8)h,明显短于A、B两组,组间差异均有统计学意义(P<0.05);C组的不良反应发生率为,略低于A、B两组,组间差异无统计学意义(P>0.05)。结论:妈富隆是治疗青春期功血的首选药物之一,值得临床推广应用。

Objective： To explore the clinical effect of three methods in the treatment of adolescent dysfunctional uterine bleeding, nethotis： Form November 2006 to June 2008 in our hospital, 120 patients of adolescent dysfunctional uterine bleeding were randomly divided into three groups, each 40 cases. A group were treated with Estradiol benzoate, Diethylstilbestrol and Medroxyprogesterone acetate, B group were treated with Premarin and Medroxyprogesterone acetate; C group was treated with Marvelon. The clinical effects of the three groups were compared and analyzed. Results： The total effective rate of A, B, C groups were 95.0%, 92.5% , 97.5% respectively, there was no statistically significant difference（ P 〉 0.05） ; the control bleeding time and bleeding time of C group were completely （42.3 ±7.2） h , （60.5 ± 5.8） h, significantly shorter than A, B groups, the differences were significant （ P 〈 0.05） ; the incidence of adverse reactions, slightly lower than A, B groups, there was no statistically significant difference（ P 〉 0.05 ）. Conclusion： Marvelon is one of the most important modality for the treatment of adolescent dysfunctional uterine bleeding, it is worth spreading.