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川崎病患儿血清中P-选择素和VEGF检测及意义

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摘要 目的探讨川崎病(KD)患儿血清P-选择素(PS)和血管内皮生长因子(VEGF)的变化及临床意义。方法将确诊为川崎病的患儿38例设为川崎病组,于治疗前后各抽取患儿外周静脉血;抽取20例正常体检儿童外周静脉血作为对照(对照组)。应用ELISA双抗体夹心法检测血清PS和VEGF值。结果川崎病组血清PS和VEGF值显著高于对照组(P<0.05);治疗前PS值显著高于治疗后(P<0.05),治疗前后VEGF值差异无显著性(P>0.05)。结论P-选择素和VEGF与KD发病有关,动态观察PS和VEGF水平变化有助于指导KD治疗和预后判断。
出处 《医药论坛杂志》 2010年第1期102-103,共2页 Journal of Medical Forum
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