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氯吡格雷治疗不稳定型心绞痛的临床观察 被引量:15

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摘要 目的观察在常规治疗的基础上加用氯吡格雷治疗不稳定心绞痛的疗效及安全性。方法不稳定型心绞痛患者83例,随机分成治疗组42例,对照组41例,治疗组在常规治疗基础上加服氯吡格雷75mg,每日一次,连续观察4周。结果1周内治疗组有效控制心绞痛发作明显优于对照组,4周内治疗组心脏事件发生情况明显低于对照组。结论在应用阿司匹林、低分子肝素等基础上加用氯吡格雷,可进一步抑制血小板的活化功能,更加有效地控制心绞痛,增加临床疗效,减少不良心脏事件的发生。
作者 曹婉燕
出处 《中国现代医生》 2010年第4期148-148,150,共2页 China Modern Doctor
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  • 1Friend M, Vucenik I, Miller M. Research pointers: Platelet responsiveness to aspirin in patients with hyperlipidaemia. BMJ, 2003, 326:82 - 83.
  • 2Gum PA, Kottke-Marchant K, Poggio ED, et al. Profile and prevalence of aspirin resistance in patients with cardiovascular disease.Am J Cardiol, 2001, 88:230 -235.
  • 3Nicholson NS, Panzer-Knodle SG, Haas NF, et al. Assessment of platelet function assays. Am Heart J, 1998, 135:S170 - S178.
  • 4Chen WH, Lee PY, Ng W, et al. Aspirin resistance is associated with a high incidence of myonecrosis after non-urgent percutaneous coronary intervention despite clopidogrel pretreatment. J Am Coll Cardiol, 2004, 43:1122 - 1126.
  • 5Wang JC, Aucoin-Barry D, Manuelian D, et al. Incidence of aspirin nonresponsiveness using the Ultegra Rapid Platelet Function AssayASA. Am J Cardiol, 2003, 92:1492 - 1494.
  • 6Bruno A, McConnell JP, Mansbach H, et al. Aspirin and urinary 11-dehydrothromboxane B2 in African American stroke patients.Stroke, 2002, 33:57 -60.
  • 7Freedman JE. CD40-CD40L and platelet function: beyond hemostasis. Circ Res, 2003, 92:944-946.
  • 8Hennekens CH, Schror K, Weisman S, et al. Terms and conditions:semantic complexity and aspirin resistance. Circulation, 2004, 110:1706 - 1708.
  • 9Antithrombotic Trialists′ Collaboration. Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. BMJ, 2002, 324:71-86.
  • 10Patrono C. Aspirin resistance: definition, mechanisms and clinical read-outs. J Thromb Haemost, 2003, 1:1710 - 1713.

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