高频超声在腕管综合征诊断中的应用探讨

Application of High-frequency Ultrasound in the Diagnosis of Carpal Tunnel Syndrome

【目的】探讨高频超声在诊断腕管综合征（CTS）中的应用价值，并进一步分析神经增粗与神经传导速度及病程的相关性，并证实高频超声在诊断CTS中的临床价值。【方法】对100例健康志愿者及63例经临床和电生理检查确诊的CST进行高频超声腕管内正中神经的检查，并记录神经的横截面积（CSA），并作CSA与神经电生理及病程的相关性分析。【结果】对照组腕管内正中神经的CSA为（8．60±2．25）mm^2，CST组CSA为（15．61±4．60）mm^2，两组相比较有显著差异（P〈0．01）。CST组CSA与神经电生理（感觉传导速速）的相关系数为-0．74（P〈0．01），与CTS病程的相关系数为0．79（P〈0．01）。【结论】高频超声在CTS的诊断有重要应用价值，其可作为CTS及周围神经检查新的形态学诊断方法。

[Objective] To explore the value of high-frequency ultrasound for the diagnosis of carpal tunnel syndrome（CTS）, and further to analyze the correlation between nerve thickening and nerve conductive velocity or the course of disease. [Methods]Sixty three patients with idiopathic CTS and 100 healthy subjects were enrolled in this study. The subjects underwent high-frequency ultrasound examination of median nerve in carpal tunnel, and the cross-sectional area（CSA） of nerve was recorded. The correlation between nerve CSA and nerve electrophysiology or the course of disease was analyzed. [Results] The CSA of the median nerves in the control group was （8.60±2.25）mm^2 and that in the CST group was （15.61±4.60）mm2 , and there was significant difference between two groups（（ P 〈0.01）. The correlation coefficient（r） between CSA and sensory nerve conduction velocity in CTS group was -0.74（ P 〈0.01） ,and that between coefficient between CSA and the course of CTS was 0.79（ P 〈0.01）. [Conclusion] High frequency ultrasound has important value for the diagnosis of CTS, and it may be as a new morphological method of the diagnosis of CTS and peripheral nerve examination.