HPLC法测定美降脂片中洛伐他汀的含量

THE DETERMINATION OF LOVASTATIN IN MEVACOV TABLETS BY-HPLC

报道HPLC法测定美降脂片中洛伐他汀的含量。流动相为甲醇-水（80：20），检测波长238nm，回收率为100．72％，RSD为1．34％，重复性RSD为0．81％。

Accurate reproducible and selective RP-HPLC method had been developed for the determination of Lovastatin in Mevacov.The column was C18-silica particles,column temperature was maintained at 35℃, the mobile phase was methanolwater(80: 20). There was good linear relationship. The average recovery was 100.72%.