白癜风患者406例临床调查分析

Clinical Investigation and Analysis on 406 Cases of Vitiligo

目的探讨白癜风患者的临床特点、发病机理,以期对临床诊断、判断疾病转归及治疗提供依据。方法对406例白癜风门诊患者进行问卷调查,对各种涉及的因素及临床表现进行统计分析。结果白癜风患者以16～20岁为发病高峰,该年龄段占发病总数的16.34%。男女发病之比为1.16:1,白癜风各型中散发型244例(60.10%),节段型8例(1.97%),有家族史者64例(15.76%)。伴晕痣28例(6.90%),伴发其他疾病者64例(15.76%)。结论白癜风发病高峰为青少年;有家族史患者发病年龄早于无家族史患者;合并晕痣患者首发年龄早于无合并晕痣患者;各型中以散发型患病人数最多,节段型最少;皮疹瘙痒和同形反应多见于进展期;部分患者白斑有自愈倾向,且自愈与精神因素关系密切。

Objective To evaluate varioues clinical characteristics of vitiligoes and explore the pathogenesis of vitiligo to provide basis for clinical dignosis and treatment. Methods Questionnaires and statistical analysis included all related factors were conducted. Results The results showed that the peak of onset was 16 to 20 years old, which occupied almost 16.34%. The ration of male and female was 1.16： 1, diverging vitiligo was in 244 （60. 10 % ） patients and segmenting vitiligo was in 8（ 1. 97% ） patients, Family history of vitiligo was present in 64（ 15.76% ） patients. Halo nevus was showed in 28（6.90% ） patients and other disease was showed in 64（ 15.76% ） vitiligo patients. Conclusions The results shows that most cases betide in youngsters and the onset age of patients who have family history is younger than the patients without familiy history. The onset age of patients who have halo nevus is younger than that without halo nevus. The number of diverging vitiligo is the most and segmenting vitiligo is the least group. Pruritic rash and isomorphic effect is related to progressive stage. Some patients can be self-heal due to spirit relaxtion .