非淋菌非衣原体性宫颈炎生殖支原体感染的检测

Detection on Nongonococcal Nonchlamydial Cervicitis Infected with Mycoplasma Genitalium

目的了解非淋菌非衣原体性宫颈炎(NGNCC)生殖支原体(Mg)感染状况并分析两者的相关性。方法采用现况研究法对158例NGNCC患者、98例非NGNCC性病门诊女性就诊者及94例健康女性进行问卷调查,并采用培养及两种PCR方法对三组人群宫颈分泌物进行Mg分离和检测。结果158例NGNCC中16例(10.13%)Mg阳性,98例非NGNCC性病门诊女性就诊者中3例(3.06%)Mg阳性,94例健康女性未检出Mg,NGNCC组Mg感染率与其他各组差异均有显著性(P<0.05)。350例受检者分为Mg阳性组和阴性组,经多因素Logistic分析,性伴数(OR=5.542,95%CI1.945～15.787)、性生活频率(OR=5.382,95%CI1.881～15.398)及既往宫颈炎史(OR=5.824,95%CI1.923～17.643)与Mg感染相关。结论NGNCC患者中存在Mg感染,Mg可能是NGNCC的致病因素之一。

Objective To obtain information on nongonococcal nonchlamydial cervicitis （NGNCC） infected with Mycoplasma genitalium （ Mg）, and analysis the relationship between the situation of epidemiology and risk factors. Methods Detected Mg by culture and PCR methods from 3 groups of different female populations： 158 NGNCC patients, 98 non-NGNCC patients and 94 healthy volunteers. At the same time, a structured questionnaire was filled by the participants for information. Results We detected Mg in 16（ 10.13% ） of 158 NGNCC patients, the positive rates of Mg in non-NGNCC patients and healthy volunteers were 3.06% （3/98） and 0.00%. Significant difference was found in each two groups （P 〈 0.05 ） except non-NGNCC patients and healthy volunteers （P 〉0.05）. The relevant factors of infection with Mg were more than 2 life -time sexual partners （ OR =5. 542,95% CI 1. 945 - 15. 787 ） , the average frequency of sexual intercourse（ OR = 5. 382, 95 % CI 1.881 - 15. 398 ） and had history of cervicitis （ OR = 5. 824, 95% CI 1. 923 - 17.643 ）. Conclusions Mg is prevalent in the cervix of women with NGNCC, it＇ s strongly associated with NGNCC.