特发性发疹性斑状色素沉着症

Idiopathic eruptive macular pigmentation

报告1例特发性发疹性斑状色素沉着症。患者男,27岁。因背部、胸部出现浅灰色色素沉着斑1个月余就诊。否认发病前有炎症性皮肤病史,无用药史。皮肤科检查:背部、胸部散在直径0.5～2.5 cm浅灰色色素沉着斑,呈均匀一致的细网纹状,皮损境界大致清楚,互不融合,表面光滑无鳞屑。皮损组织病理检查:基底层黑素增多,基膜完整,未见细胞空泡化变性,真皮有较多噬黑素细胞。4个月后随访,约75%色素斑已消退或颜色变淡。诊断:特发性发疹性斑状色素沉着症。

A 27-year-old male presented with light gray macules on the back and chest for more than one month. There was no history of preceding inflammatory dermatosis, and no medication had been taken prior to the eruption. Physical exami nation revealed a few roughly demarcated, light gray macules involving the back and chest. The diameters of the lesions varied from 0.5 to 2.5 cm. The macules were smooth with fine texture and no scale. Skin biopsy showed increased pigmentation of the basal layer in an otherwise normal epidermis and basal membrane. Melanophages scattered in the papillary dermis. A 4-month follow-up found that 75% pigmented macules were resolved or lightened. All these comformed to the diagnosis of idiopathic eruptive macular pigmentation.