深圳市野生动物驯养人员弓形虫感染的血清学调查

Serological survey of Toxoplasma gondii infection in wild animal breeders in Shenzhen

目的了解深圳市野生动物驯养人员的弓形虫感染状况。方法采用整群抽样方法,对深圳动物园的野生动物驯养人员进行血清CAg、IgM和IgG的ELISA检测,并统计学分析其感染特征。结果共调查动物园野生动物驯养人员204人,CAg循环抗原、IgM抗体和IgG抗体的阳性率分别为2.45%、4.90%和9.31%,三项合并后的总阳性率为13.73%,高于我国各地的人群平均阳性率。在同一动物园不同工作区域工作的驯养人员的弓形虫感染率没有显著性差异,但女性的IgG阳性率和总阳性率比男性高,工龄较短者的IgM阳性率比工龄较长者高,而工龄较长者的IgG阳性率比工龄较短者高。结论动物园野生动物驯养人员是弓形虫病防治的重点人群,野生动物在弓形虫的传播中起着重要的媒介作用。

Objective To survey the infectious status of Toxoplasma gondii in wild animal breeders in Shenzhen. Methods wild animal breeders were clusterly sampled and detected for CAg,IgM and IgG of by ELISA,and then the features of infection were analyzed. Results There 204 breeder cases in Shenzhen wild animal zoo were surveyed. The positive rates of CAg, IgM and IgG of Toxoplosma gondii among them were 2.45%, 4.90% and 9.31% respectively, higher than that of the common population. There was no significant difference among those working in different animal zones. The infection rate of female breeders was significantly higher than that of male breeders.The group with shorter length of service shared higher IgM positive rate and lower IgG positive rate when compared with the groups with longer length of service. Conclusion Wild animal breeders are high risk population for Toxoplasma gondii infection and effective preventive measures be taken.