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SIRS患儿血清白细胞介素-6含量检测的临床意义

Clinical significance of serum IL-6 in children with the systemic inflammatory response syndrome
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摘要 目的探讨白细胞介素-6(Interleukin-6,IL-6)在小儿全身炎症反应综合症(systemic inflammatory response Syndrome,SIRS)过程中所起的作用和临床意义。方法30例小儿SIRS患者为SIRS组,30例门诊普通发热儿童为发热对照组,另外30例门诊正常体检儿童为健康对照组,采用ELISA法测定受检者血清IL-6含量。结果实验组患儿血清IL-6含量显著高于发热对照组和健康对照组,而发热对照组和健康对照组的IL-6含量无显著性差异。结论IL-6参与了小儿全身炎症反应综合症(SIRS)的发生发展,IL-6的含量测定可作为SIRS的辅助诊断指标。 Objective To investigate the role and clinical significance of interleukin-6 (IL-6) in ehidmn with the systemic inflammatory response syndrome (SIRS). Methods The serum levels of IL-6 in 30 children with SIRS.30 children with normal fever and 30 healthy children were determined by ELISA. Results The serum level of IL-6 in children with SIRS was significantly higher as compared to that of control group, No significant difference was found between normal fever children and that in healthy children. Conclusion IL-6 may play an important role in the pathogenesis of SIRS.
出处 《中国热带医学》 CAS 2010年第4期482-482,491,共2页 China Tropical Medicine
基金 深圳市科技计划资助项目(医疗卫生类) 项目编号:200702078
关键词 白细胞介素-6 全身炎症反应综合症(SIRS) 儿童 Interleukin-6 (IL-6) Systemic inflammatory response syndrome( SIRS) Children.
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  • 1Watson RS,Carcillo JA,Linde-Zwirble WT,et al.The epidemiology of severe sepsis in children in the United States[J].Am J Respir Crit Care Med,2003,167(5):695-701.
  • 2Goldstein B,Giroir B,Randolph A,et al.International pediatric sepsis consensus conference:definitions for sepsis and organ dysfunction in pediatrics[ J ].Pediatr Crit Care Med,2005,6 (1):2-8.
  • 3Randolph A.The purpose of the 1st International sepsis forum on sepsis in infant and children[J].Pediatr Crit Care Med,2005,6(Suppl):s1-s2.
  • 4Hayden WR.Sepsis terminology in pediatrics[J].J Pediatr,1994,124(4):657-658.
  • 5Barton P,Kalil A,Nadel S,et al.Safety,pharmacokinetics,and pharmaco-dynamics of drotrecogin alfa(activated)in children with severe sepsis[J].Pediatrics,2004,113(1):7-17.
  • 6Brili R J,Goldstein B.Pediatric sepsis definitions:past,present,and future[J].Pediatr Crit Care Med,2005,6(3 Suppl):s6-s8.
  • 7Carcillo JA,Field AI,Task Force Committee Members.Clinical practice parameters for hemodynamic support of pediatric and neonatal patients in septic shock[J].Crit Care Med,2002,30(6):1365-1378.
  • 8Levy MM,Fink MP,Marshall JC,et al.2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference [ J ].Crit Care Med,2003,31(4):1250-1256.
  • 9李春盛.关于多脏器功能障碍综合征的几个问题[J].中国危重病急救医学,2000,12(6):326-327. 被引量:27

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