急性胰腺炎合并肝损害152例临床分析

Clinical analysis of 152 patients with acute pancreatitis complicated by liver injury

目的探讨急性胰腺炎(AP)患者肝脏损害的临床特点。方法对该院2006年5月至2008年5月收治的236例急性胰腺炎患者的临床资料进行回顾性分析。结果236例急性胰腺炎患者中有152例出现肝损害,占64.4%,其中轻型胰腺炎(MAP)56.5%(104/184),重症胰腺炎(SAP)92.3%(48/52),SAP较MAP肝功能损害发生率高,损害程度更明显,差异具有统计学意义(P<0.05)。结论急性胰腺炎大多伴有肝损害,其损害程度与胰腺炎病情轻重程度相关。

Objective To explore the clinical characters of acute pancreatitis with liver injury. Methods To analyze the data of 236 patients with acute pancreatitis admitted to our hospital from May 2006 to May 2008 retrospectively. Results 152（64.4%） out of 236 patients had liver injury. 104 （56.5 %） of 184 patients with mild acute pancreatitis and 48 （92.3% ） of 52 patients with severe acute pancreatitis had liver injury. The incidence and damage level of liver injury were much higher in the patients with severe acute pancreatitis than those with mild acute pancreatitis（P〈0.05）. Conclusion Most patients with acute pancreatitis bare liver injury. The degree of liver injury correlates to severity of acute pancreatitis.