急性ST段抬高型心肌梗死患者介入治疗门-囊时间的影响因素研究

Influential Factors of Door-to-balloon Times with Primary Percutaneous Coronary Intervention in Patients with Acute ST-elevation Myocardial Infarction

目的探讨急性ST段抬高型心肌梗死(STEMI)患者急诊介入治疗门-囊时间(患者入院至首次球囊扩张的时间)的影响因素。方法回顾性分析潞河医院2008年1月—2009年1月连续收治的198例急诊介入治疗的STEMI患者的门-囊时间的影响因素。按门-囊时间的不同将患者分为两组:A组(≤120min)和B组(>120min),应用logistic回归分析影响门-囊时间的因素。结果单因素分析筛选出12个影响门-囊时间的因素(P均<0.05);12个因素进行多因素非条件Logistic回归分析发现5个变量与门-囊时间明显相关(P均<0.05)。结论多数STEMI患者的门-囊时间超过指南要求,临床因素和院内机制与长门-囊时间相关,应当建立起有效的机制来降低院内延迟。

Objective Analyze the influential factors of the door - to - balloon time in patients with Acute ST - elevation Myocardial Infarction. Methods We retrospectively analyzed the door - to - balloon time of the 198 patients with STEMI who underwent procedures of PCI during 1 , 2008 and 1 , 2009. Twelve different factors were analyzed with Logistic regression to select the factors with obvious influence on the door - to - balloon time. Results 5 variables were found to have obvious correlation with the door - to - balloon time. Conclusion Most of the patients whose door - to - balloon times are prolonged beyond the requirement of the guideline. Clinical characteristics and institutional factors are associated with the prolonged door - to - balloon time, It is essential to set up effective in - hospital organizations to reduce hospital delay time to meet with the desirable therapeutic time window.