竹叶石膏汤加减配合兰索拉唑治疗反流性食管炎疗效观察

Clinical Effect Observation of Modified Lophatheri and Gypsi Fibrosi Decoction and Lansoprazole on Reflux Esophagitis

目的:观察竹叶石膏汤加减配合兰索拉唑治疗反流性食管炎(RE)的临床疗效。方法:将94例RE患者随机分为两组,治疗组口服竹叶石膏汤和兰索拉唑,对照组口服兰索拉唑,4周为1疗程,观察两组中医症状疗效、胃镜下食管黏膜炎症的变化。结果:治疗组临床症状改善情况总有效率为93.75%,胃镜下黏膜炎症改善总有效率为83.33%;对照组临床症状总有效率为86.96%,胃镜下黏膜炎症改善总有效率为71.74%,治疗组治疗临床症状改善及胃镜下黏膜炎症改善均优于对照组(P<0.05)。结论:竹叶石膏汤和兰索拉唑配合治疗反流性食管炎有良好疗效。

Objective ： To observe the clinical effect of Modified Lophatheri and Gypsi Fibrosi Decoction on reflux esophagitis （RE）. Method： 94 cases with reflux esophagitis were randomly divided into two groups. Treatment group was treated with Lophatheri and Gypsi Fibrosi Decoction and Lansoprazole, and control group was done with lansoprazole. A course of treatment included 4 weeks. Then the symptoms and endoscopic esophageal mucosal inflammatory changes were observed and recorded. Result： The total effective rate of improvement of clinical symptoms was 93.75% , and that of change of endoscopic esophageal mueosal inflammation was 83.33%. In control group, the total effective rate of improvement of clinical symptoms was 86.96% , and that of change of endoscopic esophageal mucosal inflammation was 71.74%. Treatment group was better than control group （P 〈 0. 05）. Conclusion： Lophatheri and Gypsi Fibrosi Decoction combined with Lansoprazole have a good effect on reflux esophagitis.