安体舒哥胶囊的急性毒性实验研究

Acute Toxicity Test of Anti-sugar Capsule

目的:观察安体舒哥胶囊的急性毒性反应,评价其安全性。方法:采用小鼠半数致死量(LD50)和最大耐受量(MTD)的测定方法,观察小鼠口服给药的急性毒性反应。结果:未测得安体舒哥的LD50,小鼠对本品口服MTD为12g/kg(约相当于临床口服用药剂量的342倍)。结论:安体舒哥胶囊毒性较低,安全性好。

Objective：To observe the acute toxicity of anti-sugar Capsule.Methods：Using LD50 and MTD method to observe the acute toxicity of anti-sugar capsule.Result：The result of LD50 of anti-sugar Capsule was not be acquired,and the MTD for mice was 12g/kg,which was about equivalent to 342 times as much as the clinical oral adults.Conclusion：The product was of less toxicity and better safety.