严重创伤时降钙素基因相关肽对心血管系统的影响
被引量:1
摘要
近年来,多脏器功能障碍综合征(MODS)已成为创伤后并发症的突出问题,其中心血管系统的损害日益引起人们的重视。严重创伤早期即存在心脏的器质性损伤和功能不全;休克期常伴有明显的心脏功能下降,除血容量、回心血量、
出处
《实用医技杂志》
2010年第3期197-198,共2页
Journal of Practical Medical Techniques
参考文献4
-
1蔡辉,董晓蕾,赵智明,姚茹冰,张永文,张群燕.压力负荷增加大鼠模型血浆内皮素与降钙素基因相关肽水平的改变[J].山西医药杂志(上半月),2009,38(11):989-991. 被引量:2
-
2林平,赵守琪,刘洋,邹海锋,徐华峰,于宏伟,于晓光.CGRP对葡萄糖诱导血管内皮细胞凋亡保护作用的研究[J].哈尔滨医科大学学报,2005,39(2):118-120. 被引量:12
-
3胡德林,李守生,汪昌荣,陈侠英,王永杰.烫伤后大鼠心肌力学变化及血清心肌肌钙蛋白T在心肌损伤诊断中的应用[J].中国烧伤创疡杂志,2002,14(1):8-11. 被引量:5
-
4黄跃生,杨宗城,迟路湘,梁晚益,闫柏刚.烧伤后“休克心”的研究[J].中华烧伤杂志,2000,16(5):275-278. 被引量:97
二级参考文献20
-
1黄跃生,黎鳌,杨宗珹.烧伤病人心肌损害及其机理的临床探讨[J].中华整形烧伤外科杂志,1993,9(2):99-102. 被引量:31
-
2黎螯.烧伤治疗学[M].北京:人民卫生出版社,1995.78.
-
3周衍淑 赵轶东 等.生理学方法与技术[M].北京:科学出版社,1984.34-66.
-
4薛纪秀,华扬,王克杰,程维涛,刘青海,魏立民,李京生.经颅多普勒超声对后腹腔镜手术中脑血流的监测[J].医学研究生学报,2007,20(7):736-738. 被引量:4
-
5de Bono DP,Yang WD.Exposure to low concentrations of hydrogen peroxide causes delayed endothelial cell death and inhibits proliferation of surviving cells[J].Atherosclerosis,1995,114(2):235-245.
-
6Schaeffer C,Vandroux D,Thomassin L,et al.Calcitonin gene-related peptide partly protects cultured smooth muscle cells from apoptosis induced by an oxidative stress via activation of ERK1/2 MAPK[J].Biochem Biophys Acta,2003,1643(1-3):65-73.
-
7Klein R.Hyperglycemia and microvascular and macrovascular diease in diabetes[J].Diabetes Care,1995,18(2):258-268.
-
8Du XL,Sui GZ,Stockklauser-Farber K,et al.Introduction of apoptosis by high proinsulin and glucose in cultured human umbilical vein endothelial cells is mediated by reactive oxygen species[J].Diabetologia,1998,41(3):249-256.
-
9Baumgartner-Parzer SM,Wagner L,Petterman M,et al.High glucose-triggered apoptosis in cultured endothelial cells[J].Diabetes,1995,44(11):1323-1327.
-
10Mizutani M,Kern TS,Lorenzi M.Accelerated death of retinal microvascular cells in human and experimental diabetic retinopathy[J].J Clin Invest,1996,97(12):2883-2890.
共引文献108
-
1孟祥熙,温海玲,郑金光,胡森.伏立诺他对严重烫伤大鼠心脏的保护作用[J].武警医学,2021(2):119-122. 被引量:1
-
2刘亚鹏(综述),李毅(审校).电击伤30例的治疗总结[J].医学信息(医学与计算机应用),2014,0(4):377-378.
-
3李晓东,黄跃生,张家平.机械牵张对缺血缺氧心肌细胞肌球蛋白重链mRNA表达的影响[J].中华烧伤杂志,2004,20(3):138-140. 被引量:18
-
4万福生,李国辉.严重烧伤后心肌损害的研究进展[J].江西医学院学报,2004,44(4):107-110. 被引量:6
-
5王正国.创伤基础研究进展[J].中华创伤杂志,2005,21(1):6-10. 被引量:34
-
6王正国.创伤的基础研究[J].生命科学,2005,17(1):88-93.
-
7万福生,李国辉.牛磺酸对严重烧伤大鼠心肌损害的保护作用[J].中华烧伤杂志,2005,21(3):173-176. 被引量:14
-
8马伟,曲年震,张建明,刘群,邢溢庆.重度烧伤患儿合并心功能不全12例原因分析[J].中华烧伤杂志,2005,21(3):225-225.
-
9谢康,黄跃生,周军利,张家平.乌司他丁对严重烫伤大鼠早期心肌损害保护作用[J].第三军医大学学报,2005,27(12):1244-1246. 被引量:15
-
10周军利,党永明,张家平,黄跃生.甘氨酸对重度烧伤后大鼠早期心肌组织的保护作用观察[J].第三军医大学学报,2005,27(12):1250-1252. 被引量:1
同被引文献19
-
1王晓云,郭霞,钱忠明.骨组织中降钙素基因相关肽阳性神经的分布及生理作用[J].中华骨科杂志,2005,25(3):185-188. 被引量:14
-
2Rosenfeld MG,Mermod JJ,Amara SG,et al.Production of a novel neuropeptide encoded by the calcitonin gene via tis-sue-specific RNA processing[J].Nature,1983,304:129-134.
-
3Toshio S,Nobuo S,Nobuyuki F,et al.Calcitoninin in a protochordate,Ciona intestinalis-the prototype of the vertebrate calcitonin/calcitonin gene-related peptide,sur-perfamily[J].FEBS,2009,276(16):4437-4447.
-
4Wang L,Shi X,Zhao R,et al.Calcitonin gene-related peptide stimulates stromal cell osteogenic differentiation and inhibits RANKL induced NF-kappaB activation,osteoclas-togenesis and bone resorption[J].Bone,2010,46(5):1369-1379.
-
5Hayashi Y,Ohtori S,Yamashita M,et al.Direct single injection of p38mitogen-activated protein kinase inhibitor does not affect calcitonin gene-related peptide expression in dorsal root ganglion neurons innervating punctured discs in rats[J].Spine,2009,34(26):2843-2847.
-
6Li J,Kreicbergs A,Bergstrom J,et a1.Site-specific CGRP innervation coincides with bone formation during fracture healing and modeling:A study in rat angulated tibia[J].J Orthop Res,2007,25(9):1204-1212.
-
7Mrak E,Guidobono F,Moro G,et al.Calcitonin gene-related peptide(CGRP)inhibits apoptosis in human osteob-lasts byβ-catenin stabilization[J].J Cell Physiol,2010,225(3):701-708.
-
8Villa I,Mrak E,Rubinacci A,et al.CGRP inhibits osteo-protegerin production in human osteoblast-like cells via cAMP/PKA-dependent pathway[J].Am J Physiol Cell Phy-siol,2006,291(3):C529-537.
-
9Granholm S,Lundberg P,Lerner UH.Expression of the calcitonin receptor,calcitonin receptor-like receptor,and receptor activity modifying proteins during osteoclast differentiation[J].J Cell Biochem,2008,104(3):920-933.
-
10Naot D,Cornish J.The role of peptides and receptors of the calcitonin family in the regulation of bone metabolism[J].Bone,2008,43(5):813-818.
-
1高文钑,张陆.老年人心脏功能的康复[J].社会福利(实务版),2013(7):39-40.
-
2周京敏.心力衰竭的自我管理[J].家庭用药,2016,0(10):9-9.
-
3张雄英,杨裕家,刘贞平.急性冠脉综合征稳定期患者血清IL-6、CRP的变化与心脏指数的关系[J].中国现代药物应用,2013,7(12):40-41. 被引量:2
-
4心肌梗死的最初48小时[J].中国农村医学杂志,2008,6(2):74-74.
-
5容永璋.乌司他丁对多脏器功能障碍综合征的治疗作用[J].实用医学杂志,2004,20(3):316-317. 被引量:3
-
6杨峰,陈斌,周泽强,韩庆.创伤后早期出现肝功能损伤的临床分析[J].腹部外科,2005,18(5):294-295. 被引量:7
-
7王慧丽,王志生,吴志新,郑丽娜,王仲健,窦凌云.创伤后早期下肢深静脉血栓130例非手术治疗分析[J].中国误诊学杂志,2010,10(10):2416-2417. 被引量:2
-
8茅尧生,吕铁,孙雪东,金烈洲,应利君,周蕾,邢海波.血必净对严重多发伤患者早期全身炎症反应的影响[J].中华创伤杂志,2008,24(1):54-56. 被引量:15
-
9陈元清,公保才旦,陈光安.44例胰腺创伤的诊断与治疗[J].青海医药杂志,2006,36(10):14-15.
-
10刘维维(编译).创伤早期血液产品和晶体复苏与严重创伤后多器官功能障碍的关系[J].中国危重病急救医学,2011,23(9):538-538.