不同给药方案治疗小儿支原体肺炎的成本-效果分析

Cost-Effectiveness Analysis of Different Medication Schemes of Mycoplasmal Pneumonia in Children

目的评价红霉素和阿奇霉素治疗小儿支原体肺炎的疗效及经济效果。方法将124例小儿支原体肺炎病例按实际用药情况分为3组,分别给予红霉素、阿奇霉素、红霉素联合阿奇霉素序贯治疗,并进行成本-效果分析。结果3组治疗方案有效率分别为76.19%,79.45%,90.00%,不良反应发生率分别为9.52%,6.85%,6.67%,成本-效果比分别为21.02,24.03,29.35。结论红霉素为小儿支原体肺炎的最佳治疗方案。

Objective To evaluate the therapeutic efficacy and pharmacoeconomic effect of erythromycin and azitromycin in the treatment of ehild mycoplasma pneumonia. Methods 124 children patients with mycoplasmal pneumonia were randomly divided into three groups, they were given erythromycin, azitromycin and sequential therapy of erythromycin combined azitromycin. Their therapeutic effects were observed and pharmaeoeconomic analysis was made. Results The effective rates of the three groups were 76. 19% ,79.45% and 90.00% ,while the adverse drug reaction rates were 9. 52%, 6.85% and 6.67%, the cost-effectiveness ratios were 21.02, 24.03 and 29.35 respectively. Conclusion The pharmaeoeconomic analysis indicates that erythromycin is the best treatment of child mycoplasma pneumonia.