期刊文献+

辛伐他汀对血小板氧化低密度脂蛋白内皮受体-1及CD40L表达影响的体外研究 被引量:2

下载PDF
导出
摘要 血小板直接参与急性冠状动脉(冠脉)综合征患者心血管事件的发生和发展。临床上使用的抗血小板药物通过不同的途径协同作用,起到防治血栓、抑制炎症、稳定斑块的作用。近来发现他汀类药物具有许多调脂作用外的多效性作用,可使心血管事件危险减少,其对血小板的作用也受到越来越多的关注。
作者 楚罗湘 吴昊
出处 《中国药物与临床》 CAS 2010年第3期336-337,共2页 Chinese Remedies & Clinics
  • 相关文献

参考文献10

  • 1Puddu P,Muscari A,Puddu GM,et al. The complexity of platelet metabolism and its contribution to atherothrombosis. Acta Cardiol, 2009,64 (2):157-165.
  • 2Chen M,Kakutani M,Naruko T,et al. Activation-dependent surface expression of LOX-1 in human platelets.Biochem Biophys Res Commun,2001,282 (1):153-158.
  • 3Hayashida K,Kume N,Murase T,et al. Serum soluble lectin-like oxidized low-density lipoprotein receptor-1 levels are elevated in acute coronary syndrome: a novel marker for early diagnosis. Circulation, 2005,112 (6):778-780.
  • 4Chen LY, Mehta P, Mehta JL. Oxidized LDL decreases L-arginine uptake and nitric oxide synthase protein expression in human platelets: relevance of the effect of oxidized LDL on platelet function. Circulation, 1996,93:1740-1746.
  • 5Marwali MR,Hu CP,Mohandas B,et al. Modulation of ADP-induced platelet activation by aspirin and pravastatin: role of lectin-like oxidized low-density lipoprotein receptor-1 ,nitric oxide,oxidative stress,and inside-out integrin signaling. J Pharmacol Exp Ther, 2007,322(3): 1324-1332.
  • 6Puccetti L, Sawamura T, Pasqui AL, et al. Atorvastatin reduces platelet-oxidized-LDL receptor expression in hypercholesterolaemic patients. Eur J Clin Invest,2005,35: 47-51.
  • 7Lutgens E,Daemen MJ. CD40-cCD40L interactions in atherosclerosis. Trends Cardiovasc Med,2002,12:27-32.
  • 8Schonbeck U,Sukhova GK,Schonbeck U,et al. Inhibition of CD40 signaling limits evolution established atherosclerosis in mice. Proe Natl Acad Sci USA,2000,97:7458-7463.
  • 9Peng DQ,Zhao SP,Li YF,et al. Elevated soluble CD40 ligand is related to the endothelial adhesion molecules in patients with acute coronary syndrome. Clin Chim Acta,2002,319(1):19-26.
  • 10Jin Y,Nonoyama S,Morio T,et al. Characterization of soluble CD40 ligand released from human activated platelets. J Med Dent Sci, 2001,48 (1):23-27.

同被引文献22

  • 1蒋连保,谢荣秋.阿司匹林+辛伐他汀对急性冠脉综合征中高敏性C-反应蛋白的影响及其意义[J].中国实用医药,2007,2(2):67-69. 被引量:5
  • 2刘永胜,沈青山,朱锐,付度关,汤永谦,陶红,李素珍,叶剑文.氟伐他汀对不稳定型心绞痛患者CRP、TNF-α和cTnI的影响[J].国外医学(心血管疾病分册),2005,32(5):307-308. 被引量:8
  • 3Malarstig A,Lindahl B,Wallentin L,et al.Soluble CIM OL levels are regulated by the 3459A 》G polymorphism and predict myocardial infarction and the efficacy of antithrombotic treatment in non-ST elevation acute coronary syndrome[J].Arterioscler Thromb Vasc Bio1,2006,26(1):1667-1673.
  • 4Libby P,Ridker PM,Maseri A.Inflammation and athleroselerosis[J].Circulation,2005,105(3):1135-1137.
  • 5高润霖,吴宁,胡大一,等.心血管病治疗指南和建议[M].北京:人民军医出版社,2006:1-3.
  • 6Cholene JM,Blumberg N,Phipps RP,et al.Developmental changes in soluble CD40 ligand[J].J Pediatr,2008,152(1):50-54.
  • 7Johnson JL.Matrix metalloproteinases:influence on smooth muscle cells and atherfselerotie plaque stability[J].Expert Rev Cardiovase Ther,2007,5(2):265-282.
  • 8Davies MJ.Reactive oxygen species,metalloproteinases,and plaque stability[J].Circulation,1998,97(24):2382-2383.
  • 9Puddu P,Muscari A,Puddu GM,et al.The complexity of platelet metabolism and its contribution to atherothrombosis[J].Acta Cardiol,2009,64(2):157-165.
  • 10中华人民共和国卫生部.中药新药临床研究指导原则[s].北京:人民卫生出版社,1993.28~30.

二级引证文献19

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部