老年慢性心力衰竭合并低钠血症临床研究

Clinical research on chronic cardiac failure with hyponatremia in aged patients

目的探讨老年慢性充血性心力衰竭(CHF)合并低钠血症较有效的防治方法。方法选择60岁以上CHF伴有低钠血症的患者60例,在常规综合治疗(利尿、ACEI、洋地黄等)基础上随机分两组,A组30例限水并给于补充高渗盐水,直至血钠恢复正常。B组30例限水但不补盐水,观察两组患者治疗前后血钠浓度及心功能改善情况。结果两组治疗后血钠浓度均有所改善,A组改善优于B组(P<0.01),心功能改善A组比B组亦有差异(P<0.05)。结论心力衰竭常合并低钠血症,治疗心衰和补钠临床上应两者兼顾,本组用3%氯化钠10ml/小时泵入静脉补充高渗盐,取得较好疗效。

Objective To discuss the effective methods of treatments and preventions of chronic cardiac failure with hyponatremia on old ages. Methods 60 cases of old ages over 60 with chronic cardiac failure with hyponatremia were divided into two groups by randomly. A groups （diuresis, ACEI, digitalis and so on） were limited water and were supplied with hypertonic saline. B groups were limited water and not supplied sodium chloride. The concentration of blood sodium and heart function improvement situation before and after treatments were detected or observed. Results After treatments, the blood sodium concentration of two groups was improved. A group＇s blood sodium concentration and the heart function were significantly improved compared with that of B groups（P〈0. 05）. Conclusion Chronic heart failure were always complicated with hyponatremia and 3 % sodium chloride with got better effects on chronic heart failure.