用斑点追踪成像评价急性心肌梗死后左室应变及其与早期重构的关系

Evaluation of myocardial strain and its relationship with early phase left ventricular remodeling in patients with AMI by using STI

目的应用斑点追踪成像技术(STI)评价急性心肌梗死患者PCI术后左室心肌应变、应变率及其与早期重构的关系。方法分析健康对照组30例与30例急性心肌梗死PCI术后患者左室LVESV、LVEDV、LVEF与峰值收缩总应变(GLS)和应变率(GSLR)的相关性。结果急性心肌梗死组左室各心肌节段峰值收缩长轴应变、应变率均不同程度低于对照组(P<0.05),且以延迟PCI术后患者为著(P<0.01);心尖两腔、三腔、四腔切面GLS、GSLR与LVESV、LVEDV和LVEF相关良好。结论用STI可测定左室心肌的应变、应变率及心肌重构情况,从而获取大量有关心肌应变方面的信息,能够快速、敏感和准确地进行心脏功能的评价。

Objective To assess the relationship between left ventricular deformation and remodeling in patients with. acute myocardial infarction （AMI） after pereutaneous coronary intervention （PCI） by using speckle tracking imaging （STI）. Methods The relationship between two dimensional strain parameters and left ventricular end systolic volume （ LVESV）, left ventricular end diastolic volume （ LVEDV）, left ventricular ejection fraction （LVEF） were analyzed. Results Comparing with normal group, SL and SrL signif- icantly decreased in MI group. There was good relationship between global strain parameters and LVESV, LVEDV and LVEF. Conclusion can quantitatively assess regional and global myocardial systolic deformation and function, and there are good correlations between two dimensional strain parameters and left ventricular remodeling indicators