护理干预对狼疮性肾炎维持治疗期病人的影响

Influence of nursing intervention on patients with lupus nephritis during maintenance therapy

[目的]探讨护理干预对狼疮性肾炎(LN)维持治疗期病人的病情影响。[方法]将2003年—2007年出院的40例LN病人随机分为干预组和对照组,每组20例,干预组出院后进行护理干预,所有研究对象均随访1年,出院后1个月、3个月、6个月、9个月、12个月各到门诊随访1次,复查补体C3、C4降低,将C3、C4降低作为LN病人病情复发的实验室指标,比较两组复发率。[结果]随着时间延长,干预组复发率明显低于对照组,差异均有统计学意义(P<0.05)。[结论]护理干预能增强病人的治疗依从性,提高病人的治疗效果和生活质量。

Objective：To probe into the influence of nursing intervention on patients with lupus nephritis during maintenance therapy.Methods：A total of 40 lupus nephritis patients discharged from 2003 to 2007 were divided into intervention and control group,20 cases each.Patients of intervention group accepted nursing intervention after discharge.All cases were followed up for one year,respectively in January,March,June,September and December in out-patient clinic.Lower blood complement C3 and C4 of all cases were rechecked as laboratory indication of lupus nephritis relapse.The relapse rate of intervention group and control group were compared.Results：With the time going,the relapse rate of intervention group patients with lupus nephritis was significantly lower than that of control group.There was significant statistical difference in terms of lupus nephritis relapse between the two groups（P〈0.05）.Conclusion：Nursing intervention for patients with lupus nephritis can relieve their psychological obstacle,increase their confidence,and enhance their treatment compliance.Therefore,it could effectively control the development of illness,let them cooperate with medical staff actively,and enhance the curative effect and quality of life of patients.