150例卵巢型子宫内膜异位症癌抗原_(125)表达特点探析

Characteristics of CA125 in 150 Patients with Ovarian Endometriosis

目的:探讨卵巢型子宫内膜异位症患者中癌抗原125(CA125)的表达特点及相关影响因素。方法:采用回顾性的研究方法,收集卵巢型子宫内膜异位症的病案150例,采用SPSS11.5软件进行统计分析。结果:150例患者中,术前测CA125者133例,64例在正常范围(48.1%),69例超过参考值(51.9%)。58例(38%)以疼痛为主诉就诊而发现卵巢囊肿和27例(18%)合并有子宫腺肌症患者,CA125表达均无统计学差异(P>0.05)。卵巢囊肿发生于左侧共111例,右侧96例。囊肿发生侧别、生育次数及流产次数对CA125表达影响差异无统计学意义(P>0.05)。结论:引起CA125变化非单一因素,CA125对于卵巢型子宫内膜异位症的敏感性为51.9%,且CA125表达与卵巢囊肿发生侧别及生育、流产次数无明显相关性。

Objective： To investigate the serum CA125 level with ovarian endometriosis and its correlative affecting factors. Methods： A retrospective analysis was performed on 150 patients who had underwent operation to diagnose ovarian endometriosis. Resets： There were 133 out of 150 cases who had tested their preoperative serum CA125 concentration, among whom, 69 cases with elevated level. The results show no difference between 58 cases with pain and 27 cases with adenomyosis. The ovarian cysts occurs on the left 111, right 96 cases respectively. The CA125 wasn＇t directly affected by the sides of endometrioma, sterility and abortion. Conclusion： The serum CA125 level was affected by multiple factors. The sensititivity of CA125 to ovarian endometriosis was 51.9%.h seems no significant correlation with sides of endometrioma, sterihty and abortion.