中药治疗卵巢癌机制研究进展

Progress on the Study of Mechanism of the Treatment on Ovarian Cancer with Traditional Chinese Medicine

卵巢癌在女性生殖器官恶性肿瘤中的发生率及病死率均较高,其治疗手段是以手术和化疗为主综合治疗。近年来发现我国传统中药或中药制剂如莪术油、苦参碱、蟾蜍毒素、人参皂苷等可发挥对卵巢癌细胞的抑制增殖、诱导凋亡、抑制肿瘤血管生成、逆转多药耐药、增强机体免疫力等抗癌作用。其作为卵巢癌的一种辅助治疗手段,有着广阔的临床应用前景。

Both the morbidity and mortality of ovarian cancer are quite high among malignant tumors of female genital organs. Its traditional therapeutic methods are surgical operation, chemotherapy, radiotherapy and combination of these methods mentioned above. In recent years, some components of traditional Chinese medicine, such as oil of zedoary turmeric, matrine, bufotoxin, ginsenoside, ete, have been found to exert antieancer actions of inhibiting proliferation, inducing apoptosis of cancer ceils, inhibiting tumor angiogenesis, reversing multidrug resistance and enhancing the immunologic function etc. As a means of adjuvant therapeutic, the bioactive components from traditional Chinese Medicine are endowed with promising future of clinical application.