期刊文献+

前哨淋巴结活检替代腋窝淋巴结清扫术在乳腺癌治疗中的应用研究 被引量:13

下载PDF
导出
摘要 目的探讨前哨淋巴结活检术(SLNB)替代腋窝淋巴结清扫术(ALND)在早期乳腺癌患者治疗中的应用价值和安全性。方法应用亚甲蓝进行SLNB,2007年3月到2009年3月始收治的临床T1~2N0M0乳腺癌病人入选本研究。所有患者均签署知情同意书,不同意SLNB替代ALND治疗为A组;同意SLNB替代ALND病人为B组,依据前哨淋巴结(SLN)状况,对SLN阴性者仅行SLNB,SLN阳性者行ALND。结果2007年3月至2009年3月共入组55例病人,29例SLNB替代ALND病人术后上肢水肿、疼痛、麻木、僵硬、肩关节活动受限及肌力减退方面的并发症均明显较ALND减少,在随访的13.7个月中,未见1例腋窝复发。结论前哨淋巴结活检术替代腋窝淋巴结清扫术术后并发症明显减少,复发率低,是早期乳腺癌患者的理想术式。
出处 《临床和实验医学杂志》 2010年第3期217-218,共2页 Journal of Clinical and Experimental Medicine
  • 相关文献

参考文献8

  • 1尼尔马,沈坤炜,韩企夏,邵志敏,吴炅,陆劲松,张家新,柳光宇,庄传经,沈镇宙,杜会锋,章英剑.乳腺癌前哨淋巴结活检30例分析[J].中国癌症杂志,2000,10(6):481-484. 被引量:23
  • 2Wada N;Imoto S;Hasebe T.Evaluation of intraoperative frazen section diagnosis of sentinel lymph node in breast cancer[J],2004(03).
  • 3Veroesi U;Pagaelli G;Vile G.A randominzed comparison of sentinel-node biopsy with routine axillary dissection in breast cancer[J],2003(06).
  • 4Shivers S;Cox C;Leight G.Final results of the Department of Defense multicenter breast lymphatic mapping trial[J],2002(03).
  • 5Haverson KJ;Taylor ME;Perez CA.Regional nodal management and patterns of failure following conservative surgery and radiation therapy for stage I and II breast cancer[J],1993(04).
  • 6McMasters KM;Giuliano AE;Ross MI;Reintgen DS,Hunt KK,Byrd DR,Klimberg VS,Whitworth PW,Tafra LC,Edwards MJ.Sentinel-lymph-node biopsy for breast cancer-not yet the standard of care[J],1998(14).
  • 7贾卫娟,苏逢锡,陈积圣.乳腺癌哨兵淋巴结活检126例的临床研究[J].中华普通外科杂志,2003,18(3):133-135. 被引量:36
  • 8沈镇宙,张亚伟.乳腺癌外科治疗的回顾和展望[J].中国实用外科杂志,2000,20(1):39-40. 被引量:133

二级参考文献16

  • 1KragDN,WeaverDL,AlexJC,etal.SurgicalresectionandradiolocalisationofthesentinelnodeinBreastCancerusingaGammaprobe[J].SurgOncol,1993,2(6):335-339.
  • 2GiulianoAE,KeganDM,GuentherJM,etal.Lymphaticmappingandsentinellymphadenectomyforbreastcancer[J].AnnSurg,1994,220:391-401.
  • 3VeronesiU,PaganelliG,GalimbertiJM,etal.Sentinalnodebiopsytoavoidaxillarydissectioninbreastcancerwithclinicallynegativelymphnodes[J].Lancet,1997,349(9069):1864-1867.
  • 4GiulianoAE,HaighPI,BrennanMB,etal.Prospectiveobservationalstudyofsentinellymphadenectomywithoutfurtheraxillarydissectioninpatientswithsentinelnodenegativebreastcancer[J].JClinOncol,2000,18(13):2553-2559.
  • 5CoxCE,PendasS,CoxJM,etal.Guidelinesforsentinelbiopsyandlymphaticmappingofpatientswithbreastcancer[J].AnnSurg,1998,227(5):645-651.
  • 6McMasterKM,TuttleTM,CarlsonDJ,etal.Sentinallymphnodebiopsyforbreastcancer:Asuitablealternativetoroutineaxillarydissectioninmulti-institutionalpracticewhenoptimaltechniqueisused[J].JClinOncol,2000,18(13):2560-2566.
  • 7O'HeaBJ,HillADK,El-shirbinyAM,etal.Sentinellymphnodebiopsyinbreastcancer:initialexperienceatmemorialsloan-ketteringcancercenter[J].JAmCollSurg,1998,186(4):423-427.
  • 8KragD,WeaverD,AskikagaT,etal.Thesentinelnodeinbreastcancermulticentrevalidationstudy[J].NEnglJMed,1998,339(14):941-946.
  • 9McintoshA,PurushothamAD.Lymphaticmappingandsentinelnodebiopsyinbreastcancer[J].BrJSurg,1998,85:1347-1376.
  • 10苏逢锡,贾渭娟,李海刚,曾韵洁,陈积圣.哨兵淋巴结活检对预测乳腺癌腋窝淋巴结转移的价值[J].中华外科杂志,2000,38(10):784-786. 被引量:37

共引文献187

同被引文献96

  • 1杨瑞,王淑君,张颖.亚甲蓝作为淋巴示踪剂的研究与展望[J].中国药剂学杂志(网络版),2009(2):65-71. 被引量:16
  • 2张键,骆成玉,林华,薛镭,杨齐,黄璇,邹日成,张泽斌,周永桥,丁毅,潘邦杰,张士淮,李晶.乳腔镜前哨淋巴结活检术的临床应用[J].中华外科杂志,2004,42(13):799-801. 被引量:19
  • 3卢崇亮.乳腺癌前哨淋巴结亚甲蓝示踪活检术的临床价值[J].中国普通外科杂志,2004,13(11):856-858. 被引量:7
  • 4Yenidunya S, Bayrak R, Haltas H. Predictive value of pathological cal parameters for axillary lymph node me- tastasis in breast carcinoma [J]. Diagnostic Pathology, 2011, 13(6) 18.
  • 5Ho VK, vander Heiden, vander LM, et al. Implementation of senti- nel node biopsy in breast cancer patients in the Netherlands [J]. European Journal of Cancer, 2008, 44(5): 683-691.
  • 6Maughan KL, Lutterbie MA, Ham PS. Treatment of breast cancer [J]. American Family Physician, 2010, 81(11): 1339-1346.
  • 7林乐军,李善春,徐志英,王永涛.核素与美蓝联合示踪在乳腺癌前哨淋巴结活检中的应用[J].山东医药,2007,47(35):73-74. 被引量:3
  • 8Dauphine CE, Khalkhali I, Vargas MP, et al. Intraoperative injection of technetium-99m sulfur colloid is effective in the detection of sentinel lymph nodes in breast cancer[J]. Am J Surg, 2006, 192(4):423-426.
  • 9Intra M, Rotmensz N, Veronesi P, el al. Sentinel node biopsy is not a standard procedure in ductal carcinoma in situ of the breast: the experience of the European institute of oneology on 854 patients in 10 years[J]. Ann Surg, 2008, 247(2):315-319.
  • 10Saleh F,Behbehani A, Asfar S, et al. Abnormal blood levesl of trace elements and metals, DNA damage, and bteastcsancer in the state of Kuwait[J]. Biological Trace Element Res, 2011, 141(1) :96-109.

引证文献13

二级引证文献108

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部