牵引成骨术治疗新生儿Pierre Robin综合征呼吸阻塞

Treatment of airway obstruction with mandibular distraction osteogenesis in Pierre Robin syndrome

目的探讨应用牵引成骨术治疗新生儿PierreRobin综合征呼吸阻塞的可行性。方法2007至2009年，用骨牵引技术治疗8例新生儿PierreRobin综合征。行双侧下颌骨斜行截骨，安置下颌骨牵张器，术后第1天开始牵引，每天3次，每次0．4mm，每天牵引1．2mm，直至延长到所需长度。结果8例患儿均按设计要求顺利完成牵引，无感染发生，无口角歪斜等面神经损伤症状。骨牵引达到预期的长度，约12～20mm，平均15mm。PierreRobin综合征患儿的阵发性青紫、吸气性呼吸困难及哺乳困难等症状均消失。结论牵引成骨术是治疗新生儿PierreRobin综合征严重呼吸阻塞比较理想的手术方法，是可行和安全的。

Objective To investigate the feasibility of mandibular distractin osteogenesis（MDO） in the treatment of airway obstruction in Pierre Robin syndrome （PRS）. Methods From 2007 to 2009, 8 newborns with PRS were treated with MDO. The mandibular distractors were fixed after bilateral oblique mandibular osteotomy. The distraction was started one day after operation, three times a day. The distraction distance was 1.2 mm per day until it reached about 12 - 20 mm（ mean 15 mm）. Results The distraction was successfully completed in 8 cases with no complication. The distraction distance reached 15 mm, as we expected. The discontinuity cyanosis, inspiratory dyspnea, dystithia were improved after distraction. Conclusions MDO is feasible and safe for the treatment of airway obstruction in PRS.