3Poutanen SM, Simor AE. Clostridium difficile-associated diarrhea in adults[J]. CMAJ,2004,171:51-58.
4Blondeau JM. What have we learned about antimicrobial use and the risks for Clostridium difficile-associated diarrhoea? [J]. J Antimicrob Chemother, 2009,63: 238-242.
5Pituch H. Clostridium difficile is no longer just a nosocomial in fection or an infection of adults[J]. Int J Antimicrob Agents, 2009,33 : 42-45.
6Zar FA, Bakkanagari SR, Moorthi KMLST, et al. A compari son of vancomycin and metronidazole for the treatment of Clostridium difficile associated diarrhea, dtratified by disease severity[J]. Clin Infect Dis, 2007,45 : 302-307.
7Thielman NM, Wilson KH. Antibiotic asscoclated colitis[A]. In: Mandell GL, Bennett JE, Dolin. R, eds. Principles and Practice of Infectious Diseases [M]. Amsterdam: Elsevier, 2005: 1249-1263.
8Oughton MT, Miller MA. Clinical and epidemiological aspects of Clostridium diffieile[J]. Clin Microbiol Newsl, 2008,30 : 87- 95.
9Musher D, Logan N, Hamill R, et al. Nitazoxanide for the treatment of Clostridium diffieile colitis[J]. Clin Infect Dis,2006,43 : 421-427.
10Leffler DA, Lamont JT. Treatment of Clostridium difficile-associated disease[J]. Gastroenterology,2009,136: 1899-1912.
8Duan Q, Zhou M, Zhu L, et al. Flagella and bacterial pathogenic- ity[J]. J Basic Microbiol, 2013, 53( 1 ) :1 -8.
9Baban S T, Kuehne S A, Barketi-klai A, et al. The role of flagella in Clostridium diecile pathogenesis:comparison between a non-ep- idemic and an epidemic strain[J]. PLoS ONE, 2013, 8(9) :1 - 12.
10Tasteyre A, Barc M C, Collignon A, et al. Role of FliC and FliD flagellar proteins of Clostridium difficile in adherence and gut colo- nization [ J ]. Infect Immun, 2001,69 ( 12 ) : 7937 - 40.