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瘦素和瘦素受体在类风湿性关节炎及其骨质疏松发病机制中的研究进展 被引量:4

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摘要 瘦素是肥胖基因编码的蛋白产物,由脂肪细胞合成并分泌的细胞因子样蛋白质类激素,由167个氨基酸组成,分子量为16000,是1994年美国Howard Hughes医学研究所首次通过ob/ob小鼠基因定位克隆发现的一种ob基因表达产物。它能限制食物热量的摄入,增加能量消耗,控制机体的体质量,在炎症、免疫方面也有重要的作用。
出处 《中国医药》 2010年第3期281-283,共3页 China Medicine
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共引文献16

同被引文献35

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  • 2邹晓军,李明娥,孙晓鹏,齐铁莉.瘦素在佐剂性关节炎大鼠血清中的表达及其在关节炎发病机制中的作用初探[J].黑龙江医药科学,2007,30(1):54-55. 被引量:4
  • 3路跃武,陈文明,陆江阳,董馨,郑毅.瘦素在类风湿关节炎中的作用机制初步探讨[J].天津医药,2007,35(3):170-172. 被引量:2
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