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骨桥蛋白与乳腺癌的关系 被引量:1

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摘要 近年来,在世界范围内乳腺癌的发病率呈逐年升高的趋势,骨桥蛋白(osteopontin,OPN)是一种分泌型、黏附性的糖基化磷蛋白。近年来的研究揭示,OPN在肿瘤细胞的黏附、移行、浸润、血管新生、凋亡以及肿瘤的微环境中起关键作用,现将其与乳腺癌的关系综述如下。
出处 《中国基层医药》 CAS 2010年第2期268-269,共2页 Chinese Journal of Primary Medicine and Pharmacy
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同被引文献7

  • 1叶春华,程志清.心肌纤维化与病毒性心肌炎[J].浙江中医学院学报,2004,28(4):85-87. 被引量:5
  • 2Collins AR, Schnee J, Wang W, et al. Osteopontin modulates angiotensin II-induced fibrosis in the intact murine heart [ J]. J Am Coil Cardiol,2004,43 (9) : 1698-1705.
  • 3Rollo EE,Hempson SJ, Bansal A, et al. The cytokine osteopontin modulates the severity of rotavirus diarrhea [ J]. J Virol,2005,79 (6) :3509-3516.
  • 4Khan SA, Lopez-Chua CA, Zhang J, et al. Soluble osteopontin inhibits apoptosis of adherent endothelial cells deprived of growth factors [ J ]. J Cell Biochem, 2002,85 (4) : 728-736.
  • 5Zohar R,Zhu B, Liu P, et al. Increased cell death in osteopontin- deficient cardiac fibroblasts occurs by a caspase-3-independent pathway [J]. Am J Physiol Heart Circ Physiol,2004,287 (4): H1730-1739.
  • 6刘立新,王宇玫,申卫东,丁秀云,王士雯.骨桥蛋白在牛主动脉平滑肌细胞体外钙化时的表达变化[J].解放军医学杂志,2009,34(4):488-489. 被引量:1
  • 7杨莉,魏玲,左文述.骨桥蛋白与乳腺癌的研究现状[J].中华肿瘤防治杂志,2011,18(14):1133-1137. 被引量:9

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