机械通气抢救急性有机磷农药中毒呼吸衰竭47例

Rescue mechanical ventilation in acute organophosphorus pesticide poisoning with respiratory failure of 47 Cases

目的探讨机械通气治疗重度有机磷农药中毒呼吸衰竭的临床意义。方法重度有机磷农药中毒呼吸衰竭患者患者83例，按是否机械通气分为治疗组47例和对照组36例。两组均常规给予洗胃、应用阿托品、氯磷定及对症支持治疗等综合措施，治疗组给予机械通气。结果治疗组抢救成功率（89％）明显高于对照组（69％）（P〈0．05）。结论早期建立人工气道机械通气是有机磷农药中毒并呼吸衰竭抢救成功的关键。

Objective To investigate the mechanical ventilation in the treatment of severe organophosphorus pesticide poisoning in the clinical significance of respiratory failure. Methods Uinical data of admitted to our hospital with severe organophosphorus pesticide poisoning respiratory failure in 83 cases were analyzed, according to whether mechanical ventilation,they were divided into treatment group （47 cases）and control group 36 cases, the efficacy were observed. Both groups were given routine gastric lavagc, atropine, PAM, and symptomatic supportive care and other comprehensive measures,the treatment group, was given an extra mechanical ventilation. Results The treatment group had significantly higher success rate of resuscitation, the two groups were significantly different （ P 〈 0. 05 ）. Conclusion Early establishment of artificial airway mechanical ventilation is a key step to rescue organophosphate pesticide poisoning, and respiratory failure to rescue key.