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急性心肌梗死患者危险因素与冠状动脉病变相关性研究 被引量:11

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摘要 目的探讨急性心肌梗死患者危险因素与冠状动脉病变程度的相关性。方法对302例急性心肌梗死患者按年龄分为三组:青年组(≤40岁)、中年组(41~64岁)、老年组(〉165岁),入选患者均行急诊或择期冠状动脉造影术。人院后测定总胆固醇、甘油三酯、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇。其中合并糖尿病61例、高脂血症50例,高血压118例、吸烟146例。结果青年组吸烟史明显高于中、老年组(P〈0.01),高血压、糖尿病低于中、老年组(P〈0.01);中年组高脂血症明显高于青、老年组(P〈0.001);青年组单支病变与中、老年组相比差异有统计学意义(P〈0.01);老年组三支病变与青、中年组相比差异有统计学意义(P〈0.01)。行多元回归分析显示高胆固醇血症为冠状动脉病变程度独立危险因素。结论急性心肌梗死多见于男性,随着年龄的增长累及冠状动脉血管支数增加;高胆固醇血症为冠状动脉病变程度独立危险因素;吸烟为青年急性心肌梗死患者的主要危险因素;高血压及糖尿病为中、老年急性心肌梗死患者主要危险因素。
出处 《中国基层医药》 CAS 2010年第3期334-335,共2页 Chinese Journal of Primary Medicine and Pharmacy
基金 内蒙古自治区包头市医药卫生科技项目(2006-55)
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