孕妇、不孕症及妇科疾病患者弓形虫感染的检测分析

Toxoplasma gondii infection in pregnant women,the infertile,and patients with gynecological diseases

目的了解弓形虫病(toxop lasmosis)血清学检测在孕妇、不孕症及妇科疾病患者中的重要性。方法用ELISA循环抗原(CAg)检测血清中弓形虫循环抗原(CAg)和特异性IgM、IgG抗体。结果孕妇、不孕症及妇科疾病患者血清中弓形虫感梁率分别为10.7%、22.6%和15.5%。而正常未孕妇女组的感染率为10.0%。结论不孕症患者组统计学与正常未孕妇女组之间差异有统计学意义(P<0.01),妇科疾病患者组也明显高于正常未孕妇女组(P<0.05),而孕妇组与正常未孕妇女组差异无统计学意义。

Objective To evaluate the significance of Toxoplasma gondii （Toxoplasmosis） serological test in pregnant women and patients with infertility, and gynecological diseases. Methods The circulating antigen （CAg） was utilized in the enzyme-linked immunosorbent assay （ELISA） to identify serum circulating antigens （CAg） and specific IgM and IgG antibodies of Toxoplasma gondii. Results The infection rates of Toxoplasma gondii were 10.7%, 22.6% and 15.5% in pregnant women, patients of infertility, and those with gynecological diseases, in contrast to 10. 0% in healthy non-pregnant women. Conclusion Statistically significant differences in the infection rates were observed between the infertile and normal non-pregnant women （ P 〈 0.01 ） ; the rate was noticeably higher in patients with gynecological disorders than that in non-pregnant women （ P 〈0.05 ）, whereas no statistical difference was present between the pregnant group and the non-pregnant group.