高分子量壳聚糖/聚氧乙烯复合纳米纤维的制备

Preparation of electrospun high molecular weight chitosan/poly(ethylene oxide) composite nanofibers

利用3%的高分子量壳聚糖(HCS)与聚氧化乙烯(PEO)以3∶1的比例溶解在50%的乙酸水溶液中,使用浓度高于临界胶束浓度的不同表面活性剂改善溶液的可纺性,借助静电纺丝技术制备了HCS/PEO复合纳米纤维。采用扫描电子显微镜(SEM)对复合纳米纤维形貌进行表征,采用傅里叶红外光谱(FTIR)方法研究了HCS、PEO及表面活性剂的相互作用,采用单纤维强力仪测试薄膜力学性能的变化,以评价使用戊二醛处理后的HCS/PEO复合纳米纤维膜的力学性能。实验结果表明PEO增强了HCS的成纤性。以胶束形式存在的表面活性剂,通过改变混合溶液中分子间的结合方式,降低溶液黏度,提高了可纺性能。戊二醛交联处理提高了复合纤维的强度。特别是阴阳离子混合表面活性剂的使用,纤维形貌最好,强度明显提高。

Nanofibers were prepared by electrospinning a mixture of high molecular weight chitosan（concentration of 3%） and poly（ethylene oxide）（PEO） at a ratio of 3∶1 in 50% aqueous acetic acid.To further improve the spinnable properties,surfactants of different charge were added at concentrations well above their critical micellar concentrations.The morphology and interaction of the composite nanofibers were characterized by Scanning Electronic Microscope（SEM） and Fourier Transform Infrared spectrum（FTIR） images,respectively.Tensile test were measured to assess the mechanical properties of the composite nanofibrous membrane in glutaraldehyde treatments.The study revealed that PEO is beneficial to the spinning properties.The composite solutions containing micellar solutions of surfactants enhanced the spinnability through modifying the molecular bond of the mixed solution and lowering its viscosity.Glutaraldehyde treatments improved the mechanical properties of the composite nanofibrous membrane.The presence of anionic-cationic surfactant resulted in the formation of smooth and high strength nanofibers.