摘要
目的通过我院AECOPD患者痰培养及药敏结果进行统计分析,了解我院目前主要耐药菌。方法对我院近期具有完整细菌学资料的COPD患者痰培养及药敏试验结果进行分析。结果792例患者痰样本中分离出病原菌280株,革兰阴性杆菌241株,占86.1%,主要为铜绿假单孢菌、不动杆菌、克雷伯杆菌、阴沟杆菌等,革兰阳性菌以金黄色葡萄球菌和表皮葡萄球菌为多。细菌药敏试验发现,不动杆菌耐药率高,以鲍曼/溶血不动杆菌明显,铜绿假单胞菌次之,革兰氏阳性球菌耐药性相对较低。结论COPD病原菌对多种抗菌药物的耐药率有上升趋势,应加强药敏测定,合理应用抗生素,减少细菌耐药菌株的产生。
Objective To provide the basis for rational application of antibiotics for the treatment of COPD by analyzing chronic obstructive pulmonary disease patients with sputum culture and sensitivity results. Methods The data was analyzed in our hospital of COPD patients with bacteriological sputum culture and sensitivity test results. Results 792 cases of patients with sputum samples of 280 pathogens were isolated ： gram-negative bacilli of 241, accounting for 86. 1% , mainly pseudomonas aerugiuosa, acinetobacter, klebsiella and so on. In the gram-positive, the bacteria staphylococcus aureus and staphylococcus epidermidis were more. Among them the drugs resistance ratio of aeinetobacter is the highest, the bacteria staphylococcus aureus is low. Conclusion COPD patients have a wide range of pathogens antimicrobial resistance which is on the rise. It should strengthen the determination of sensitivity, and reasonable application of antibiotics to reduce the emergence of drug-resistant strains of bacteria.
出处
《临床肺科杂志》
2010年第4期491-492,共2页
Journal of Clinical Pulmonary Medicine
关键词
慢性阻塞性肺疾病
痰培养
药敏试验
耐药率
chronic obstructive pulmonary disease
sputum cultivation
sensitivity test
drugs resistance
