摘要
本实验采用每天颈背部皮下注射125mg/kg的D-半乳糖造小鼠亚急性衰老模型,同时经灌胃给药0.7g/kg·d,1.4g/kg·d红景天软胶囊,通过对CAT、SOD、GSH—Px活力、MDA含量以及胸腺和脾指数的测定,观察红景天软胶囊对D-半乳糖所致衰老小鼠衰老作用的影响。结果表明红景天软胶囊可显著提高衰老小鼠血SOD、CAT及GSH-Px活性以及胸腺和脾指数,降低血MDA水平,表明红景天软胶囊具有良好的抗衰老的效果。
In order to observe the anti-aging effect of Rhodiola Capsule on aging mice induced by D-gal. We determined the activity of CAT in blood and activities of SOD and GSH-PX in serum, the content of MDA in serum with senile model caused by D-gal ( 125 mg,/kg · d) and meanwhile administered with Rhodiola Capsule of 0.7 g/kg · d, 1.4 g/kg · d orally. It was found that Rhodiola Capsule car. obviously increase the activation of CAT, SOD; GSH-PX; thymus index and spleen index in blood, and decrease the level of MDA of aging mice. The results proofed that Rhodiola Capsule had the obvious effect on antisenility.
出处
《天然产物研究与开发》
CAS
CSCD
2009年第B05期223-226,共4页
Natural Product Research and Development