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脓毒症凝血系统功能变化与预后关系的探讨

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摘要 目的探讨脓毒症患者凝血功能的变化与预后的关系,为临床诊治提供科学依据。方法将2008年1月~2009年f0月入住我院重症监护病房的脓毒症患者分为生存组32例,死亡组10例,分别检测血小板计数(PLT)、D-二聚体(DD)、凝血酶原时间(PT)、凝血酶时间(TT)、活化部分凝血活酶时间(AP1T)、纤维蛋白原(Fbg),分析比较两组患者的差异及主要凝血指标与病情严重度(APACHEⅡ评分)的关系。结果脓毒症患者死亡组与生存组比较血小板计数减少(P〈005)、活化部分凝血活酶时间延长(P〈0.01)、D-二聚体升高(P〈0.01)、纤维蛋白原降低(P〈0.01),PLT、AFIT、DD与APACHEⅡ评分有相关性。结论脓毒症时存在凝血功能紊乱,动态监测其凝血指标对判断患者的预后及评估病情严重程度有重要意义。
出处 《中国保健营养(下半月)》 2010年第2期14-15,共2页 China Health Care & Nutrition
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